Publications by authors named "David A Eichmann"

Article Synopsis
  • A study investigated the prevalence of vestibular disorders in patients with COVID-19 compared to those without the virus using data from the National COVID Cohort Collaborative database.
  • Results showed that individuals with COVID-19 were significantly more likely to experience vestibular disorders, with the highest risk associated with the omicron 23A variant (OR of 8.80).
  • The findings underscore the need for further research on the long-term effects of vestibular disorders in COVID-19 patients and implications for patient counseling.
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Objective: Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical data are abundant, these are largely inaccessible to outside researchers. Statistical, machine learning, and causal analyses are most successful with large-scale data beyond what is available in any given organization.

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RNA interference (RNAi) serves as a powerful and widely used gene silencing tool for basic biological research and is being developed as a therapeutic avenue to suppress disease-causing genes. However, the specificity and safety of RNAi strategies remains under scrutiny because small inhibitory RNAs (siRNAs) induce off-target silencing. Currently, the tools available for designing siRNAs are biased toward efficacy as opposed to specificity.

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