Macrodystrophia Lipomatosa of the Foot: A Case Report of MRI and Histologic Findings Including Pacinian Corpuscle Abnormalities.

Case: A 37-year-old man presented with pain and macrodactyly of a toe. Imaging and histology demonstrated findings consistent with macrodystrophia lipomatosa (MDL). We compared our findings with control tissue obtained from an identical site of a fresh-frozen cadaveric foot from the same anatomical site.

Cancer cell metabolic plasticity in migration and metastasis.

Metabolic reprogramming is a hallmark of cancer metastasis in which cancer cells manipulate their metabolic profile to meet the dynamic energetic requirements of the tumor microenvironment. Though cancer cell proliferation and migration through the extracellular matrix are key steps of cancer progression, they are not necessarily fueled by the same metabolites and energy production pathways. The two main metabolic pathways cancer cells use to derive energy from glucose, glycolysis and oxidative phosphorylation, are preferentially and plastically utilized by cancer cells depending on both their intrinsic metabolic properties and their surrounding environment.

Knee Osteoarthritis with Chronic Quadriceps Tendon Rupture Treated with Total Knee Arthroplasty and Extensor Mechanism Allograft Reconstruction: A Case Report.

Case: A 51-year-old male construction worker with a history of chronic quadriceps tendon rupture presented with no active knee extension and tricompartmental knee osteoarthritis. He underwent simultaneous total knee arthroplasty and extensor mechanism allograft reconstruction. At 4 years postoperatively, the patient had pain-free knee function and active extension.

The GI fluoroscopy suite in the early twenty-first century.

Since the application of cross-sectional imaging to the examination of the gastrointestinal tract, dramatic changes have occurred in the modern gastrointestinal fluoroscopic suite. Besides the great decrease in use of fluoroscopy, the types of fluoroscopic examinations requested and performed nowadays are different from those of just 2 or 3 decades ago. This paper will review the recent history and the current uses of fluoroscopy in adults at the beginning of the twenty-first century, illustrated by case images and utilization data from a large academic medical center.