Publications by authors named "David A Bomback"
Background: To investigate the clinical safety and efficacy of ViBone Viable Bone Matrix (VBM), a next generation cellular bone matrix allograft that comprises all three essential bone-forming components: osteogenic, osteoinductive, and osteoconductive factors, and is optimized to enhance cell viability and bone formation.
Methods: This was a multi-center, prospective, post-market study evaluating the safety and efficacy of ViBone VBM in patients undergoing 1-3 level anterior cervical discectomy and fusion or lumbar interbody fusion surgery. Patients were evaluated at baseline, 6-month, and 12-month follow-up clinically and radiographically.
Background Context: The transpsoas lateral lumbar interbody fusion (LLIF) technique is an effective alternative to traditional anterior and posterior approaches to the lumbar spine; however, nerve injuries are the most reported postoperative complication. Commonly used strategies to avoid nerve injury (eg, limiting retraction duration) have not been effective in detecting or preventing femoral nerve injuries.
Purpose: To evaluate the efficacy of emerging intraoperative femoral nerve monitoring techniques and the importance of employing prompt surgical countermeasures when degraded femoral nerve function is detected.
Background Context: Video-assisted thoracoscopic surgery (VATS) is a new technique that allows for access to anterior spinal pathology using a minimally invasive approach. Proponents of this procedure argue that anterior thoracic spine surgery can be performed with the same accuracy and completeness as is possible by the conventional open approach but through much smaller skin and muscle incisions. Advantages of VATS include decreased blood loss, shorter hospital stay, and improved cosmesis.
View Article and Find Full Text PDFStudy Design: Posterolateral lumbar spine fusions in athymic rats.
Objectives: To compare spine fusion rates of two different osteoinductive products.
Summary Of Background Data: Many osteoinductive bone graft alternatives are available.
Article Synopsis
- The study investigates the effectiveness of a posterolateral lumbar fusion model using athymic rats, which are devoid of a thymus to reduce inflammatory responses.
- A total of 40 athymic rats underwent spinal fusions with either autografts or no grafts, and outcomes were assessed at 3 and 6 weeks through various methods.
- Results showed low fusion rates, with no spontaneous fusions in rats without grafts, indicating that the lack of a thymus does not negatively impact the success of autograft spinal fusions.