Publications by authors named "Dave Segall"
DNA damage reduces heterogeneity and coherence of chromatin motions.
Proc Natl Acad Sci U S A
July 2022
Article Synopsis
- Chromatin, which is the material that DNA is made of, moves around in different ways that can affect how our genes work, especially when DNA gets damaged.
- In yeast, when there are breaks in DNA, chromatin spreads out more, but in more complex organisms (like humans), it's more complicated.
- When DNA is damaged, the movement of chromatin changes; it slows down far from the damage but moves more freely near the break, which helps the cell to repair the damage and avoid problems with DNA structure.