Publications by authors named "Dave Payne"

Article Synopsis
  • - The global effort to fight the SARS-CoV-2 pandemic has led to some promising preventive measures, but there's still a need for affordable and effective treatments.
  • - Researchers are using a new high-capacity screening method called VirtualFlow to find inhibitors that can target SARS-CoV-2 effectively.
  • - This innovative approach involved searching nearly 1 billion molecules against 40 different target sites related to the virus and its host, including both viral enzymes and important protein interactions.
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), previously known as 2019 novel coronavirus (2019-nCoV), has spread rapidly across the globe, creating an unparalleled global health burden and spurring a deepening economic crisis. As of July 7th, 2020, almost seven months into the outbreak, there are no approved vaccines and few treatments available. Developing drugs that target multiple points in the viral life cycle could serve as a strategy to tackle the current as well as future coronavirus pandemics.

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Background: Contact with livestock wastewater on farms and in communities can pose a risk to human and animal health.

Methods: This cross-sectional study was conducted in 180 households and 24 pig farms (96 wastewater samples) to explore information about pig production, livestock waste management, antibiotic use, and to analyze antibiotic residues and microbial contamination, respectively.

Results: Of the 120 households raising pigs, biogas systems were the most commonly used to treat animal waste (70%), followed by compositing (19%), and the remaining respondents discharged waste directly into drains or ponds (11%).

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