Domains involved in calcineurin phosphatase inhibition and nuclear localisation in the African swine fever virus A238L protein.

The African swine fever virus A238L protein inhibits calcineurin phosphatase activity and activation of NF-kappaB and p300 co-activator. An 82 amino acid domain containing residues 157 to 238 at the C-terminus of A238L was expressed in E. coli and purified.