Publications by authors named "Daulat Bikram Khadka"
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Synopsis of recent research by authors named "Daulat Bikram Khadka"
- Daulat Bikram Khadka's recent research primarily focuses on the structural design and synthesis of novel compounds, targeting various nuclear receptors and neurotransmitter systems, specifically in relation to their roles in disorders like cancer and neuropsychiatric conditions.
- His findings include the discovery of pyrazolamides as ERRγ inverse agonists, the efficient synthesis of aryl stannanes, and the development of several classes of potent monoamine neurotransmitter reuptake inhibitors, showcasing innovations in drug design and synthesis methodologies.
- Additionally, his work highlights the potential therapeutic applications of these compounds, such as in osteoblast differentiation for bone regeneration and as inhibitors against key targets like topoisomerase I and PPARγ, thereby contributing to advancements in pharmacological treatments.
