Biomarkers.

Background: The present study examined OSA using an objective home sleep test in 81 adults with DS (aged 25 ∼ 61 years) and evaluated associations between sleep-disordered breathing problems and biomarkers of AD pathology (PET Aβ and tau) and symptomology (cognitive performance and depressed mood).

Method: As part of the ABC-DS study, participants completed a 2.5-hour battery of cognitive measures and underwent MRI and PET imaging scans and a blood draw.

Comparative analysis of electrodermal activity metrics and their association with child behavior in autism spectrum disorder.

Researchers are increasingly utilizing physiological data like electrodermal activity (EDA) to understand how stress "gets under the skin." Results of EDA studies in autistic children are mixed, with some suggesting autistic hyperarousal, others finding hypoarousal, and yet others detecting no difference compared to non-autistics. Some of this variability likely stems from the different techniques used to assess EDA.