Publications by authors named "Dasom Kim"

Photoelectrochemical CO reduction reaction (PEC-CO2RR) into multicarbon (C and C) products is one of the most favorable paths for converting and utilizing atmospheric CO. Although Cu-based photocathodes have unique features that can convert CO into value-added products, they have limited selectivity. In this study, we established the Cu-based heterostructure by introducing the CuO (111) phase on the surface of Cu/Cu(OH) nanorods array (CNA) while integrating Pd cocatalyst to improve the selectivity of the C products via PEC-CO2RR.

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Article Synopsis
  • The study aimed to explore alcohol consumption norms and attitudes towards alcohol regulation among 1,001 adults in Seoul, analyzing how these factors relate to preferred regulatory policies.
  • Younger, male, single, and heavier drinkers showed a more favorable attitude towards drinking and less support for regulation.
  • A negative correlation was found between attitudes towards drinking and support for regulation, suggesting that those favoring lower alcohol consumption were more open to restrictive policies, indicating the need to address drinking norms for effective alcohol control policies.
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Background: Capsular contracture is one of the most common and severe complications after implant-based breast reconstruction. Recently, prepectoral implant-based breast reconstruction using acellular dermal matrix (ADM) has become an alternative to subpectoral implant-based reconstruction. However, risk factors for capsular contracture associated with recent prepectoral reconstruction trends are not well refined yet.

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Lymphedema is known to affect as many as 140 to 250 million people worldwide. Approximately 99% of lymphedemas are secondary cases after lymphadenectomy, radiation, or parasite infection. There has been no accurate estimate of the lymphedema population size in South Korea.

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Eukaryotic cells can synthesize formyl-methionine (fMet)-containing proteins not only in mitochondria but also in the cytosol to some extent. Our previous study revealed substantial upregulation of N-terminal (Nt)-fMet-containing proteins in the cytosol of SW480 colorectal cancer cells. However, the functional and pathophysiological implications remain unclear.

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Background: In recent years, Korean society has increasingly recognized the importance of nurses in the context of population aging and infectious disease control. However, nurses still face difficulties with regard to policy activities that are aimed at improving the nursing workforce structure and working environment. Media coverage plays an important role in public awareness of a particular issue and can be an important strategy in policy activities.

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In the present study, a total of 30 species of Phyllonorycter Hbner, 1822 (Lepidoptera: Gracillariidae: Lithocolletinae) in Korea are recognized and enumerated. Among them, two species (Phyllonorycter phallustenuis sp. nov.

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  • This study investigates how often confirmatory tests are performed on women with abnormal cervical cytology in South Korea and what factors influence this rate.
  • The analysis reveals that while abnormal Pap smear rates initially increased, they plateaued after 2016, and the rate of confirmatory tests significantly rose over the years from 2011 to 2021, especially for atypical cases.
  • Key factors influencing the likelihood of undergoing confirmatory tests include the severity of the abnormal results, age, and location, while economic status did not significantly impact this likelihood.
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Background: Meyrick, 1916 is a relatively small genus within the family Gracillariidae, consisting of nine species worldwide, including five species in Korea.

New Information: In this study, we recognise five species belonging to the genus Meyrick, 1916 from Korea. Amongst them, one species, Liu, Wang & Wang, 2018, is reported for the first time in Korea.

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Introduction: Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with adverse human health outcomes. To explore the plausible associations between maternal PAH exposure and maternal/newborn metabolomic outcomes, we conducted a cross-sectional study among 75 pregnant people from Cincinnati, Ohio.

Method: We quantified 8 monohydroxylated PAH metabolites in maternal urine samples collected at delivery.

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Background: Oncogenic KRAS mutation, the most frequent mutation in non-small cell lung cancer (NSCLC), is an aggressiveness risk factor and leads to the metabolic reprogramming of cancer cells by promoting glucose, glutamine, and fatty acid absorption and glycolysis. Lately, sotorasib was approved by the FDA as a first-in-class KRAS-G12C inhibitor. However, sotorasib still has a derivative barrier, which is not effective for other KRAS mutation types, except for G12C.

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Background: The central line has been frequently used for drug and nutrition supply and regular blood sampling of patients with chronic diseases. However, this procedure is performed in a highly sensitive area and has several potential complications. Therefore, peripherally inserted central catheters (PICC), which have various advantages, are being extensively used.

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Background: Small cell lung cancer (SCLC) has an exceptionally poor prognosis; as most of the cases are initially diagnosed as extensive disease with hematogenous metastasis. Therefore, the early diagnosis of SCLC is very important and may improve its prognosis.

Methods: To investigate the feasibility of early diagnosis of SCLC, we examined exosomal microRNAs (miRNAs) present in serum obtained from patients with SCLC.

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AXL is a member of TAM receptor family and has been highlighted as a potential target for cancer treatment. Accumulating evidence has uncovered the critical role of the AXL signaling pathway in tumor growth, metastasis, and resistance against anti-cancer drugs, as well as its association with cancer immune escape. However, the function of AXL as a manipulator of the immune system in the tumor microenvironment (TME) remains unclear.

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Introduction: Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is a rare tumor that arises in the myometrium of the uterus. It is regarded as an intermediate malignant tumor according to the recent World Health Organization classification. Few studies have reported the radiologic findings of STUMP, and the differentiation of STUMP from leiomyoma remains controversial.

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Ferroptosis can be induced by inhibiting antioxidant enzymes GPX4 or system Xc, increased intracellular iron concentrations, and lipid peroxidation. Recently, it has been suggested that ferroptosis can be an effective way to induce cancer cell death, although the specific relevance and mechanism of ferroptosis have not been fully elucidated. Here, we investigated the anticancer effects of ferroptosis inducers erastin and RSL3 on non-small cell lung cancer (NSCLC) cells.

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Introduction: Clear cell hepatocellular carcinoma (HCC) is a rare subtype of HCC. Histologically, clear cell HCC is characterized by the cytoplasmic accumulation of glycogen with a clear cell appearance, constituting > 80% of tumor cells. Radiologically, clear cell HCC demonstrates early enhancement and washout similar to conventional HCC.

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Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of 9 cancer types and 1241 normal control samples, and also a reference dataset for background variant filtering based on 20,529 low-depth healthy samples. An external cfDNA dataset consisting of 208 cancer and 214 normal control samples is used for additional evaluation.

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Article Synopsis
  • N-formyl methionine (fMet)-containing proteins are found in bacteria, mitochondria, plastids, and cytosol, but are not well studied due to detection challenges.
  • A new anti-fMet rabbit polyclonal antibody was developed using a specific peptide to recognize Nα-terminally formylated proteins across different species.
  • This antibody enables researchers to better understand the roles and mechanisms of these underexplored proteins in various organisms.
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Ubiquitin (Ub) is highly conserved in all eukaryotic organisms and begins at the N-terminus with Met and Gln. Our recent research demonstrates that N-terminally (Nt-) arginylated Ub can be produced in the yeast Saccharomyces cerevisiae. However, the existence of Nt-arginylated Ub in multicellular organisms remains unknown.

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Purpose: This study identified the effects of applying information and communication technologies (ICT) to the health management of older adults aged 65 or older.

Methods: Older adults registered at public health centers were provided with the health management app "Health Today" and a smart speaker for 6 months to perform assigned healthcare missions. The program was conducted for 6 months by dividing participants into two groups: one that received both the health management app and the smart speaker, and another that used only the health management app.

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Protein mutations alter protein-protein interactions that can lead to a number of illnesses. Mutations in lamin A (LMNA) have been reported to cause laminopathies. However, the proteins associated with the LMNA mutation have mostly remained unexplored.

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  • The study investigates how respiratory motion affects the accuracy and complications of CT-guided percutaneous transthoracic needle biopsy (PTNB) for lung nodules during quiet breathing.
  • Researchers analyzed 426 cases and found that nodules with greater respiratory motion (>1 cm) showed similar diagnostic sensitivity and accuracy compared to those with less motion, despite more technical challenges.
  • The study concludes that while respiratory motion can complicate the procedure, it does not negatively impact the diagnostic outcomes or complication rates associated with PTNB.
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In this study, 29 species of Hübner, 1825, belonging to the family Gracillariidae, were recognized in Korea. Among these, three species, i.e.

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Purpose: To investigate the longitudinal effects of adequate exercise, defined as an exercise duration of ≥150 min/week by the World Health Organization (WHO), on cognitive function in middle-aged adults.

Methods: This study was a longitudinal panel analysis using secondary data obtained from the Korean Longitudinal Study of Aging (KLoSA) database, with 4,825 participants registered and comprising five rounds of survey data in 2-year intervals from 2010 to 2018. The participants were divided into the adequate exercise (≥150 min/week), deficient exercise (<150 min/week), and no exercise groups according to the WHO definition, and their cognitive decline over the 8-year period was analyzed.

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