Detection of basilar artery dissection by ultrasound.

We report a case of a 45-year-old woman with unusual headache 1 week before admission. After cerebrovascular ultrasound, a basilar artery dissection was supposed despite the normal neurologic, cerebrospinal fluid, and computed tomography findings. On a follow-up color-coded duplex sonography (1 month after the onset), reperfusion was detected in the vertebral and basilar arteries, but residual high-grade stenosis of the basilar artery was also present.

Free-floating thrombus in stroke patients with nonstenotic internal carotid artery-an ultrasonographic study.

Background: There are multiple causes of free-floating thrombus (FFT) formation in carotid arteries. The purpose of this study was to evaluate the incidence and natural history of FFT in nonstenotic internal carotid arteries of patients with acute ischemic stroke.

Methods: During a 50-month period, 3,200 consecutive patients with acute ischemic stroke were evaluated for internal carotid artery stenosis and the presence of FFT by color-coded duplex ultrasonography.

Bioequivalence of a novel high-dose oral formulation of alpha-dihydroergocryptine.

The plasma pharmacokinetics of alpha-dihydroergocryptine (DHEC, CAS 14271-05-7) were investigated in 24 patients with Parkinson disease after the administration of repeated oral doses of 40 mg DHEC twice daily by means of a novel 40 mg DHEC tablet (Almirid 40 mg test T) and an established 20 mg DHEC tablet (Almirid 20 mg - reference R). The trial was conducted according to a randomised, controlled, open, within-subject cross-over design; steady-state was established by means of a stepwise up-titration from 5 to 40 mg b.i.

The brain scintiscan with iodine-123-ioflupane to diagnose early Parkinson's disease; seven months follow up. First results in Bulgaria.

The aim of this study was to evaluate the brain scintiscan images with (123)I-ioflupane for the diagnosis of patients with early Parkinson's disease (PD). Sixteen patients were studied, nine males and seven females, aged between 38-81 y (mean age: 64 y). All patients underwent thyroid blocking by oral administration of 120 mg potassium iodide before and 24 h after the intravenous (iv) injection of 110-185 MBq/70 kg patient's weight, of (123)I-ioflupane.

Conduction block--the diagnostic value in the early stage of Guillain-Barre syndrome.

Immune-mediated segmental demyelination is the basic pathomorphological substrate of the Guillain-Barre syndrome (GBS). The aim of the study is to determine the diagnostic value of the conduction block in the early stage of GBS, as well as its changes during of the development of the disease. Sixteen patients with GBS were examined.

[Atraumatic procedures in common abdominal operations].

The surgical tactics and technical improvements are discussed against the background of personal experience with some common abdominal operations, among which the appendectomy variant leaving the cecum intra-abdominally and using chain retrograde ligature in some cases, with choice of access according to the requirements of the individual case. Special attention is called to retrocecal extraperitoneal complications and Meckel's diverticulum--clinical picture and operative tactics. Emphasis is laid on the advantages of intestinal anastomoses--latero-lateral variant, termino-terminal technique in colo-colostomy and possibilities of latero-terminal sigmoidorectoanastomosis.

[Pathophysiologically advisable operations on the biliary-hepatic-pancreatic system].

Nowadays, the modern operative treatment of biliary-hepatic-pancreatic diseases is pathogenetically substantiated. In lithiasis and cholecystitis removal of the gallbladder should be undertaken only after assessment of the patency and output of the biliary tree (i.e.

[Liver resections and operations in portal hypertension viewed via the experience of our practice].

After listing the indications for liver resection, the operative technique used is discussed with a special reference to an original modification implemented in practice. The case material is made of 52 liver resections and 6 lobectomies with a favourable outcome. In one lobectomy with subtotal proximal resection jejunogastroplasty is performed, supplemented by isolated antireflux anisoperistaltically interposed invagination esophagojejunostomy, duplicated by suturing its two portions.

[Radionuclide study of disorders of esophageal motility in patients with diabetic polyneuropathy].

Radionuclide method was used to examine transport function of the esophagus in 24 patients with diabetes mellitus and symmetric distal polyneuropathy. 99mTc-+sulfur colloid was employed as a radiopharmaceutical agent. The movement of radioactivity was elucidated visually with the aid of a gamma-chamber.

[A radionuclide study of esophageal motility disorders in patients with diabetic polyneuropathy].

The radionuclide method was used to examine transport function of the esophagus in 24 patients suffering from diabetes mellitus and symmetric distal polyneuropathy. 99Tc-sulfocolloid was employed as a radiopharmaceutical agent. Radioactivity movement was visualized by means of a gamma chamber.

[Late deficiency states in patients with a surgically treated stomach].

37 patients with partial stomach resection because of peptic ulcer, performed 5 to 28 years before, were studied. In 29 patients the serum vitamin B12 and folic acid levels were determined by radioimmunoassay. In 19 patients several hematologic indices--hemoglobin, serum iron, erythrocyte morphology, proteinogram--were determined, too.

[Late complications in patients having undergone a gastric resection].

A total of 37 patients who had undergone partial gastrectomy for duodenal or gastric ulcers, were investigated. The postoperative periods ranged from 5 to 28 years. All the patients were subjected to comprehensive clinical and neurologic examinations.

[Changes in the mitral echogram in ischemic heart disease].

The patients with ischemic heart disease (IHD) have usually elevated end diastolic pressure (in the left ventricle (LVEDP). Such a change in LVEDP and to a certain extent the pathological ventricular contraction and the reduced compliance of the LV wall lead to definite pathological changes in the mitral echogram. The values, obtained by statistical-variation analysis, of the amplitudes and the velocity diastolic parameters of the mitral echogram in the group of the healthy subjects were compared with those of 60 patients with chronic IHD.

[Determination of the pulse wave spreading rate by the 1st rheographic derivative].

Besides via sphygmography, the propagation rate of pulse wave (PRPW) could be determined also by a synchronous record of volume and differential rheograms of aorta and limbs. For that purpose, 110 clinically healthy subjects were examined, grouped in 3 age groups (15-40, 41-60 and over 60). Synchronous rheographic records from the initial and terminal part of descending aorta with determination of PRRPW along vessels of elastic type (Ve) and from the arch of the aorta-left forearm--for vessels of muscular type (Vm) were recorded.

[Additional right pectoral leads].

A total of 476 subjects were examined. The control group was of 220 (170 healthy males and 50 females) and 256 cardiac patients (180 males and 76 females); with right ventricle loading -- 106 (6-70 years), left ventricle - 35 (average age 38), disturbed intraventricular conductivity -- 76, and myocardial infarction -- 39 patients. The additional right pectoral leads (ARPL) -- V3R--V8R are included in the extended ECG programme for investigation (routine 12 ECG leads, left precordial -- V7--V9 and Nehb).

[Differential diagnostic value of the aVR lead].

The one-pole peripheral AVR lead reflects the changes in the electromotive power of the heart in a frontal plane in a reverse (mirror) image. In 620 subjects with healthy hearts, with the aid of an extended ECG method; the variants of the auricle-ventricle complex in AVR lead in norm and the separate heart positions, were studied. The pathologically changed P-wave was established to be presented by its typical forms (P-mitrale, P-pulmonale), but in a mirror image in AVR lead.