Non-traumatic rupture of spleen: can splenectomy be applied selectively?

Background: Non-traumatic rupture of the spleen is a rare condition. It can occur in a pathological spleen caused by any of a variety of diseases. For yet unknown reasons this condition may sometimes involve an apparently normal spleen as well.

Comparison of HER-2 overexpression in primary breast cancer and metastatic sites and its effect on biological targeting therapy of metastatic disease.

HER-2 overexpression, a predictive marker of tumour aggressiveness and responsiveness to therapy, occurs in 20-30% of breast cancer. Although breast cancer is a heterogeneous disease, HER-2 measurement is carried out in primary tumour. This study aims to evaluate HER-2 overexpression in primary and metastases and its effect on treatment decisions.

Unusual presentation of angiocentric T-cell lymphoma mimicking perianal abscess.

Background: Subcutaneous angiocentric T cell is a common form of cutaneous lymphoma localized within subcutis mimicking lobular panniculitis. It is rarely manifested as perianal skin lesion.

Objective: To suggest that perianal T-cell lymphoma is a rare entity that should be included in the differential diagnosis of perianal infiltrate mimicking perianal abscess.

Spillage of stones from the gallbladder during laparoscopic cholecystectomy and complication of a retroperitoneal abscess mimicking gluteal abscess in elderly patients.

Gallbladder perforation during laparoscopic cholecystectomy with spillage of bile and gallstones occurs in a substantial percentage of patients (up to 40%). We report the case of a 77-year-old woman who presented with fever of unknown etiology and a complication of retroperitoneal abscess mimicking a gluteal abscess with gallstones and clips the abscess. Spillage of gallstones from perforation of the gallbladder is a well-recognized complication of laparascopic cholecystectomy, especially several months after the initial surgery, as in the reported case.

Ketamine enhances local anesthetic and analgesic effects of bupivacaine by peripheral mechanism: a study in postoperative patients.

Patients with unilateral (n = 14) and bilateral (n = 4) herniorrhaphy participated in this study. With bilateral herniorrhaphy, at the end of the surgery, the wound was infiltrated with a solution of bupivacaine 0.5% and ketamine 0.

Alfentanil dose-response relationships for relief of postoperative pain.

The aim of this study was to characterize within-patient alfentanil dose-response curves for the relief of spontaneous postoperative pain and to test the closeness of relationships 1) between pain intensity and alfentanil analgesic requirements, and 2) between alfentanil requirements for analgesic and nonanalgesic (sedative and miotic) effects. The effects of alfentanil were studied in 23 patients after elective abdominal surgery. During a 40- to 60-min testing session, the patient received two intravenous (i.