Publications by authors named "Dashini Pillay"

Background: Automated haematology analysers such as the Sysmex XN-3000 (Sysmex Corporation, Kobe, Japan) utilise white blood cell (WBC) flags to identify quantitative and qualitative abnormalities. Owing to clinical and biological factors, the sensitivity and specificity of the flags vary when compared to microscopy, the gold-standard method for assessing peripheral blood smear (PBS) morphology.

Objective: This study assessed the performance of the Sysmex XN-3000 haematology analyser in comparison to PBS microscopy for the detection of WBC abnormalities.

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Introduction: In acquired hemophilia A (AHA), the body produces auto-antibodies against Factor VIII. Although AHA is rare, with an incidence of 1.5 patients/1 million population/year, there is a strong association with human immunodeficiency virus (HIV) infection.

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Background: The recommendation for coagulation blood samples is to centrifuge at 4000 revolutions per minute (rpm) for 15 min to produce platelet-poor plasma before analysis. Rapid centrifugation, defined as centrifuging samples at higher speeds for shorter durations, could potentially reduce turn-around times (TAT), provided sample integrity is maintained.

Objective: This study assessed the impact of rapid centrifugation on routine coagulation assay results.

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Background: Referral of samples for the work-up of haematological disorders from remote laboratories can result in a delay in analysis.

Objective: The stability of the full blood count (FBC), differential count (DIFF), reticulocyte and peripheral blood smear (PBS) morphology during extended storage was evaluated.

Methods: Forty blood samples stored in ethylenediaminetetraacetic acid (EDTA) were analysed on an ADVIA® 120 haematology analyser.

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