[Pulmonary regulation of fibrinogen levels in acquired heart defects with pulmonary hypertension].

Fibrinogen levels and aortic and pulmonary-artery blood pressure were measured in 143 patients with acquired heart diseases and pulmonary hypertension and in 60 control patients. The lungs were shown to participate in the regulation of fibrinogen levels both in the controls and patients with heart diseases, as reflected in the deposition-balance-mobilization phases by positive, zero, negative arterio-venous difference of fibrinogen levels. The association between the metabolic and hemodynamic functions of the lungs is particularly obvious, if pressure gradients (pulmonary-capillary and bronchial perfusion ones), making for blood inflow into the alveolar-capillary region, are examined.

[The relationship between the state of the pulmonary circulation and indices of cerebral gas exchange in patients with acquired heart defects].

The author studied the state of hemeostasis in normals and in patients with acquired heart insufficiency. By means of bloody methods of triple probe samples of the blood inflow and outflow from the brain, and by biochemical methods they also studied 22 normals and 100 patients with acquired heart insufficiency for interrelations between the gas metabolism indices and acid-base equilibrium of the central pulmonary hemodynamics. As a results it was established that the brain blood flux in patients with acquired heart insufficiency in different degrees of pulmonary hypertension is adequate to the metabolic requirement of the brain in oxygen and corresponds to identical indices in normals.