Problem And Background: During the COVID-19 pandemic, there was substantial reconfiguration of maternity care services, affecting both users and healthcare providers (HCPs), in the United Kingdom (UK) and globally.
Aim: To further our understanding of the impact of maternity service reconfigurations in the UK, from the perspective of maternity HCPs.
Methods: Scopus, MEDLINE, EMBASE, CINAHL, PsycINFO and the Cochrane COVID Study Register were searched for relevant studies reporting qualitative data from the UK, published in English between 01 June 2021 and 30 September 2023.
The development and synthesis of notably targeted and colorimetric sensor based on an azomethine compound for the distinct recognition of Cu and CN ion individually in an aqueous dimethyl formamide solution is performed. In the presence of CN and Cu, the sensor BTZ showed impressive colorimetric changes, going from pale yellow to orange and pale yellow to dark yellow, respectively. In the meantime, FL spectrum (Cu) and UV-vis spectroscopy (CN/Cu) were used to assess the sensing features.
View Article and Find Full Text PDFInhibition of vascular endothelial growth factor receptor 2 (VEGFR-2) facilitates potent antiangiogenic and anticancer responses. In this regard, the development of effective pharmacophores, i.e.
View Article and Find Full Text PDFFerroptosis has been recognized as an iron-based nonapoptotic-regulated cell death process. In the quest of resisting the unyielding vehemence of triple-negative breast cancer (TNBC), herein we have showcased the ferroptosis-inducing heteroleptic [], [], and [] complexes, enabling them to selectively target "sialic acid", an overexpressed cancer cell-surface marker. The open-circuit potential (OCP) measurements in live cancer cells revealed the specific interaction between TNBC and the complexes, whereas control experiments with normal cells did not exhibit such interactions.
View Article and Find Full Text PDFTo improve transitions in care, a new patient navigation (PN) program was introduced to support older adults with complex care needs transition from hospital to home. The patient navigator is a community social worker embedded in the hospital's care teams. A cohort observational design was used to conduct the study by analysing the patient navigator's clinical notes and hospital's administrative data to describe the characteristics of patients, scope of the patient navigator's activities, and patient outcomes.
View Article and Find Full Text PDFThe lithium salt of 6-amino hexanoic acid (Li-AHA) was melt-mixed with poly(vinylidene fluoride) (PVDF), wherein the Li-AHA concentration was varied between 1-15 wt% with the aim of establishing hydrogen bonding between the NH functionality of Li-AHA and the -CF moieties of PVDF. This was followed by compression-moulding as well as solution-casting to make PVDF/Li-AHA composite thin films. FTIR analysis established interactions between the -CF groups in PVDF with amine functional moieties of Li-AHA.
View Article and Find Full Text PDFA Patient Navigation (PN) model of care was introduced in a large metropolitan hospital in Ontario (Canada) to support transitions in care for older adults in 2019. The patient navigator is a community social worker or "community transitional lead" embedded in the hospital's in care teams to assist with discharge planning and provide follow-up care to older adults, their families, and/or care partners for up to 90 days. Initially, the PN program supported acute care patients and has since expanded in the Emergency Department and Reactivation Care Centre.
View Article and Find Full Text PDFMaternal vaccination during pregnancy, in general and against COVID-19 infection, offers protection to both mother and baby, but uptake remains suboptimal. This study aimed to explore the perceptions regarding COVID-19 vaccination in pregnancy, particularly for marginalised populations and those living with social or medical complexity. A total of 96 semi-structured in-depth interviews were conducted with 40 women, 15 partners, 21 HCPs, and 20 policy makers, across all four nations of the United Kingdom (UK), discussing their lived experience of utilising, delivering, or developing policy for COVID-19 vaccination in pregnancy during the pandemic.
View Article and Find Full Text PDFRu(II)-complexes have been recognised as promising in treating cancer. However, targeted delivery is an important facet to augment the efficiency of drugs. Consequently, this article portrays the construction of biotinylated-MWCNTs as an SMVT-guided nano-platform for the precise delivery of our previously-developed potent Ru(II)-scaffold, making it more effective against MCF-7 cells.
View Article and Find Full Text PDFAn experimental setup has been developed for the simultaneous measurement of the Hall coefficient (RH) and electrical conductivity (σ) of thermoelectric (TE) specimens in the temperature range of 300-700 K. The van der Pauw geometry is utilized for the RH and σ measurements. The sample holder geometry has been designed for diverse TE specimen dimensions and easy sample mounting.
View Article and Find Full Text PDFBackground: Testing positive for COVID-19 was associated with higher rates of detrimental psycho-social and physical health outcomes. The COVID-19 pandemic caused unprecedented disruption to everyday life. This included major reconfiguration of maternal, child, and perinatal mental health and care services and provision.
View Article and Find Full Text PDFObjectives: This study aimed to evaluate the effect of introduction and subsequent withdrawal of the Results-based Financing for Maternal and Newborn Health Initiative (RBF4MNH) in Malawi on utilisation of facility-based childbirths, antenatal care (ANC) and postnatal care (PNC).
Design: A controlled interrupted time series design was used with secondary data from the Malawian Health Management Information System.
Setting: Healthcare facilities at all levels identified as providing maternity services in four intervention districts and 20 non-intervention districts in Malawi.
Background: Maternity care services in the United Kingdom have undergone drastic changes due to pandemic-related restrictions. Prior research has shown maternity care during the pandemic was negatively experienced by women and led to poor physical and mental health outcomes in pregnancy. A synthesis is required of published research on women's experiences of maternity care during the latter half of the COVID-19 pandemic.
View Article and Find Full Text PDFIntroduction Generalized ligamentous laxity (GLL) is defined as an increased range of motion across multiple joints in an individual beyond the mean range of motion in the general population, with a reported prevalence between 5% and 15%. It becomes less common with age and is more common in females and in the lower limbs. Musculoskeletal injury (MSI) is damage to musculoskeletal systems, usually due to strenuous activity.
View Article and Find Full Text PDFHealthcare workers are at risk of adverse mental health outcomes due to occupational stress. Many organizations introduced initiatives to proactively support staff's psychological well-being in the face of the COVID-19 pandemic. One example is the STEADY wellness program, which was implemented in a large trauma centre in Toronto, Canada.
View Article and Find Full Text PDFBackground and objective Total knee arthroplasty (TKA) is a highly successful surgical procedure. However, there is a lack of consensus about whether to resurface the patella or not. This study was aimed at evaluating the outcome of patellar resurfacing in terms of a decrease in the incidence of anterior knee pain after TKA and assessing whether patellar resurfacing is beneficial in improving functional outcomes.
View Article and Find Full Text PDFIn recent years, bismuth-rich Mg(SbBi) ( = 0.5-0.8) compositions have generated significant interest due to their excellent thermoelectric (TE) performance near room temperature, making them potential applicants for recovery of low-grade waste heat.
View Article and Find Full Text PDFThis study demonstrates a cost-effective, thin, multifunctional composite coating system with outstanding thermal insulation for thermal management and heat shield applications, such as roofs, as well as outstanding resistance to corrosion. The hydrophobic multifunctional epoxy composite coating systems were designed with surface-modified fillers to impart both reduced heat conduction and high infrared reflectance in a thin coating with a 65-100 μm dry film thickness (DFT). With a judicial combination of hollow microspheres (HMS) activated and modified with silica (sHMS) and stearic acid-modified TiO (sMO), the developed composite coating attained the highest thermal insulation property with a temperature drop of 21-31 °C at different distances below the coated panel, which is superior to the values of temperature drop reported earlier.
View Article and Find Full Text PDFFucoidan is linked to a variety of biological processes. Differences in algae species, extraction, seasons, and locations generate structural variability in fucoidan, affecting its bioactivities. Nothing is known about fucoidan from the brown alga , its anti-inflammatory properties, or its inherent mechanism.
View Article and Find Full Text PDFACS Appl Mater Interfaces
October 2023
MgSbBi solid-solutions represent an important class of thermoelectric (TE) materials due to their high efficiency and variable operating temperature range. Of particular significance for midtemperature applications is the MgSbBi composition whose superior thermoelectric (TE) performance is attributed to the complex conduction band edge in conjunction with alloy dominated phonon scattering. In this work, we show that microstructure also plays a significant role in lowering the lattice thermal conductivity which in turn affects the overall TE performance (change in peak zT values between 1.
View Article and Find Full Text PDFThe liver is in charge of a wide range of critical physiological processes and it plays an important role in activating the innate immune system which elicits the inflammatory events. Chronic ethanol exposure disrupts hepatic inflammatory mechanism and leads to the release of proinflammatory mediators such as chemokines, cytokines and activation of inflammasomes. The mechanism of liver fibrosis/cirrhosis involve activation of NLRP3 inflammasome, leading to the destruction of hepatocytes and subsequent metabolic dysregulation in humans.
View Article and Find Full Text PDFACS Appl Mater Interfaces
May 2023
In the medium temperature (600-850 K) range, NaPbTe is a highly efficient p-type thermoelectric compound. Device fabrication utilizing this compound for power generation demands highly stable low-contact resistance contacts with metal electrodes. This work investigates the microstructural, electrical, mechanical, and thermochemical stability of NaPbTe-metal (Ni, Fe, and Co) contacts made by a one-step vacuum hot pressing process.
View Article and Find Full Text PDF