Application of the Sydney System for Classification and Reporting Lymph Node Cytopathology to Assess the Risk of Malignancy and its Diagnostic Accuracy.

Background: Fine-needle aspiration cytology (FNAC) of the lymph nodes is the first-line evaluation of lymphadenopathy of unknown etiology. For better diagnostic clarity and proper communication to clinicians, the Sydney System was proposed in 2020 for the performance, classification, and reporting of lymph node cytopathology. The present study was conducted to analyze the diagnostic performance and risk of malignancy (ROM) associated with each of the diagnostic categories of the proposed Sydney System.

I-JAMM (II)-Therapeutic Apheresis Practices in Preconditioning of ABO-Incompatible Kidney and Liver Transplants in India.

ABO-incompatible transplantations are increasingly gaining relevance with advancements in therapeutic modalities, thus allowing patients to receive timely solid organ transplants. Therapeutic apheresis (TA) procedures remain instrumental as a preconditioning measure to enable such transplants. This survey was undertaken to find out current trends and practices of TA across major transplant centers in India.

Strongyloides Hyperinfection Syndrome Following Immunosuppressant Therapy for COVID-19: A Case Report With Literature Review.

Strongyloides hyperinfection and disseminated infections are usually associated with immunosuppression; these severe manifestations occur in a minority of cases. The use of immunosuppressants such as corticosteroids and Baricitinib for treating COVID-19 pneumonia can be responsible for patients' immunosuppression and cause Strongyloides hyperinfection syndrome. The chance increases when the patient belongs to countries or regions where chronic infection with Strongyloides is more prevalent.

Pooled Multicenter Safety Analysis of Lupin's Intravitreal Biosimilar Ranibizumab (Ranieyes) in Chorioretinal Vascular Diseases.

Introduction: This study aims to evaluate the ocular and systemic safety profiles of intravitreal biosimilar ranibizumab Ranieyes (Lupin Pharmaceuticals, Mumbai, India) in real-world clinical settings across multiple chorioretinal vascular diseases, including neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) in adults.

Methods: We conducted a retrospective, consecutive, interventional, uncontrolled multicenter study using data from three hospital networks in India. A total of 1401 eyes received 2194 injections of Ranieyes between June 2022 and November 2023.

A circularly polarized graphene based wideband 1 × 2 array antenna for terahertz spectrum applications.

A graphene-based 1 × 2 array antenna with circular polarization for terahertz applications is prescribed in this article. Initially, a novel concept of a folded quarter wave impedance transformer is utilized in the design process of a single element for minimizing the overall antenna size. The opposite corners of the patches have been truncated and structural modifications are performed with the insertion of four flower-shaped slots along with an additional circular slot for achieving a much-improved reflection coefficient and better impedance bandwidth.

Wireless sensor network-based machine learning framework for smart cities in intelligent waste management.

Environmental safety is one of the key issues that are directly related to a country's prosperity One of the most fundamental aspects of a sustainable economy is waste management and recycling. Better recycling safety and efficiency may be achieved via the use of intelligent devices rather than manual effort. In this research, we describe a machine learning-based architecture for smart trash collection and sorting using the Internet of Things and wireless sensor networks.

A national survey of current immunohematologic testing practices for the diagnosis of autoimmune hemolytic anemia in India.

Autoimmune hemolytic anemia (AIHA) is a common term for several disorders that differ from one another in terms of etiology, pathogenesis, clinical features, and treatment. Management of patients with AIHA has become increasingly evidence-based in recent years. While this development has resulted in therapeutic improvements, it also carries increased requirements for optimal diagnosis using more advanced laboratory tests.

'Old is gold' does conventional test tube method still reign supreme? An immuno-haematological survey of anti-D detection and titration in ante-natal cases among major hospitals across India.

Introduction: Anti-D detection and titration plays a major role in RhD negative antenatal cases both, for monitoring maternal as well as fetal status as well as initiation of early therapeutic interventions, such as intra-uterine transfusions (IUT) to improve maternal as well as fetal morbidity and mortality and reduce the adverse effects of haemolytic disease of fetus and newborn (HDFN). We conducted a survey focusing on the policies and procedures of anti-D detection and titration among major tertiary care centres across India.

Methodology: The survey was drafted by a working group of transfusion medicine and immunohematology specialists from six different centres in India.

Chasmophyte associated stress tolerant bacteria confer drought resilience to chickpea through efficient nutrient mining and modulation of stress response.

In the present study, ten (10) selected bacteria isolated from chasmophytic wild Chenopodium were evaluated for alleviation of drought stress in chickpea. All the bacterial cultures were potential P, K and Zn solubilizer. About 50% of the bacteria could produce Indole-3-acetic acid (IAA) and 1-aminocyclopropane-1-carboxylate (ACC) deaminase.

M--M mediated denaturation resistant P2 tetramer on the infected erythrocyte surface of malaria parasite imports serum fatty acids.

In , DNA replication, and asynchronous nuclear divisions precede cytokinesis during intraerythrocytic schizogony. Regulation of nuclear division through the import of serum components was largely unknown. At the trophozoite stage, ribosomal protein P2 (PfP2) is exported to the infected erythrocyte (IE) cytosol and the surface as a denaturation-resistant tetramer.

Induction of thrombotic thrombocytopenic purpura by dengue virus infection in a critical patient: Role of therapeutic plasma exchange.

Thrombotic thrombocytopenic purpura (TTP) secondary to dengue fever is a very unusual occurrence. Both conditions are fatal and can result in significant mortality and morbidity if left untreated. In this case, we present a young lady who suffered dengue fever followed by microangiopathic anemia, thrombocytopenic purpura, and altered sensorium.

Recent Advancements in Bioelectronic Medicine: A Review.

Bioelectronic medicine is a multidisciplinary field that combines molecular medicine, neurology, engineering, and computer science to design devices for diagnosing and treating diseases. The advancements in bioelectronic medicine can improve the precision and personalization of illness treatment. Bioelectronic medicine can produce, suppress, and measure electrical activity in excitable tissue.

Presentation and outcome of central serous chorioretinopathy with and without pachychoroid.

Background: The present study compared clinical features and outcomes of central serous chorioretinopathy (CSC) with and without pachychoroid.

Methods: It was a retrospective, longitudinal, record-based study which included eyes with CSC. Patients underwent spectral domain optical coherence tomography and differentiated between pachychoroid and non-pachychoroid groups.

Coherent X-ray Scattering Reveals Nanoscale Fluctuations in Hydrated Proteins.

Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investigate the nanoscale stress-relaxation in hydrated lysozyme proteins stimulated and probed by X-ray Photon Correlation Spectroscopy (XPCS). This approach allows us to access the nanoscale dynamics in the deeply supercooled regime ( = 180 K), which is typically not accessible through equilibrium methods.

Polymeric copper(ii) and dimeric oxovanadium(v) complexes of amide-imine conjugate: bilirubin recognition and green catalysis.

An exceptionally simple amide-imine conjugate, ()-'-(4-(diethylamino)-2-hydroxybenzylidene)-4-methylbenzohydrazide (L), derived by the condensation of 4-methyl-benzoic acid hydrazide (PTA) with 4-(diethylamino)-2-hydroxybenzaldehyde was utilized to prepare a dimeric oxo-vanadium (V1) and a one-dimensional (1D) copper(ii) coordination polymer (C1). The structures of L, V1 and C1 were confirmed by single crystal X-ray diffraction analysis. The experimental results indicate that V1 is a promising green catalyst for the oxidation of sulfide, whereas C1 has potential for a C-S cross-coupling reaction in a greener way.

A Novel Design of Spike-Shaped Miniaturized 4 × 4 MIMO Antenna for Wireless UWB Network Applications Using Characteristic Mode Analysis.

In this article, a 4 × 4 miniaturized UWB-MIMO antenna with reduced isolation is designed and analyzed using a unique methodology known as characteristic mode analysis. To minimize the antenna's physical size and to improve the isolation, an arrangement of four symmetrical radiating elements is positioned orthogonally. The antenna dimension is 40 mm × 40 mm (0.

5G Technology in Healthcare and Wearable Devices: A Review.

Wearable devices with 5G technology are currently more ingrained in our daily lives, and they will now be a part of our bodies too. The requirement for personal health monitoring and preventive disease is increasing due to the predictable dramatic increase in the number of aging people. Technologies with 5G in wearables and healthcare can intensely reduce the cost of diagnosing and preventing diseases and saving patient lives.

Studies of Performance of CsTiIBr (Where x = 0 to 6)-Based Mixed Halide Perovskite Solar Cell with CdS Electron Transport Layer.

The present research work represents the numerical study of the device performance of a lead-free CsTiIBr-based mixed halide perovskite solar cell (PSC), where x = 1 to 5. The open circuit voltage (V) and short circuit current (J) in a generic TCO/electron transport layer (ETL)/absorbing layer/hole transfer layer (HTL) structure are the key parameters for analyzing the device performance. The entire simulation was conducted by a SCAPS-1D (solar cell capacitance simulator- one dimensional) simulator.

Kinetics of Covid-19 antibodies in terms of titre and duration among healthcare workers: A longitudinal study.

Background Most individuals with Covid-19 infection develop antibodies specific to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the dynamics of these antibodies is variable and not well-studied. We aimed to determine the titres of naturally acquired antibodies over a 12-week follow-up.

An insight to the internal quality control of blood components separated using the latest whole blood collection and processing systems: Experience from a tertiary care hospital blood transfusion service in Eastern India.

Background: With blood component therapy becoming the standard of care in transfusion medicine globally, the quality control (QC) of these components has become a routine and mandatory program in all blood centers. Extensive utilization of blood components has been observed in our multidisciplinary tertiary care hospital. We use quadruple bag systems and automated component extraction facilities for collection and processing of whole blood (WB).

Application of flow cytometry in transfusion medicine: The Sanjay Gandhi Post Graduate Institute of Medical Sciences, India experience.

The application of flow cytometry (FC) is diverse and this powerful tool in used in multiple disciplines such as molecular biology, immunology, cancer biology, virology, and infectious disease screening. FC analyzes a single cell or a particle very rapidly as they flow past single or multiple lasers while suspended in buffered solution. FC has a great impact in the field of transfusion medicine (TM) due to its ability to analyze individual cell population and cell epitopes by sensitive, reproducible, and objective methodologies.

Investigations on Stub-Based UWB-MIMO Antennas to Enhance Isolation Using Characteristic Mode Analysis.

In this article, very compact 2 × 2 and 4 × 4 MIMO (Multiple-Input and Multiple output) antennas are designed with the help of Characteristics Mode Analysis to enhance isolation between the elements for UWB applications. The proposed antennas are designed with Characteristic Mode Analysis (CMA) to gain physical insight and also to analyze the dominant mode. To improve isolation and minimize the mutual coupling between radiating elements, elliptical shaped stubs are used.

Change in attitude and help-seeking pattern of caregivers and patients with mental disorders in the community - Recent findings from India.

Unlabelled: Knowledge of factors related to patients' and primary caregivers' health-seeking behaviour is required for a complete early intervention for the management of mental illness. Previous research has found that men are more likely to seek care and that a considerable proportion of patients seek help from native healers before obtaining psychiatric help. The goal of this study was to see if there had been any changes in the paths to psychiatric care, as well as the socio-demographic characteristics that were linked to early help-seeking behaviour among patients with mental illnesses in metropolitan eastern India.