Publications by authors named "Daryl Prichard"
Article Synopsis
- The study evaluates the cost-effectiveness of exome sequencing (ES) and genome sequencing (GS) for diagnosing genetic conditions in critically ill infants and children.
- It compares various diagnostic strategies, including standard of care testing and combinations of ES and GS, measuring their costs and the quality-adjusted life years (QALYs) they provide.
- Findings suggest that first-line GS is the most cost-effective for diagnosing infants, while ES is a close alternative when GS isn’t an option; for children, GS could also be cost-effective under specific conditions regarding long-term prognosis.
