Publications by authors named "Darya Slonova"
Metagenomics is a powerful tool to study marine microbial communities. However, obtaining high-quality environmental DNA suitable for downstream sequencing applications is a challenging task. The quality and quantity of isolated DNA heavily depend on the choice of purification procedure and the type of sample.
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- Lanthipeptides are a type of peptides produced by ribosomal synthesis and later modified, classified into five groups based on structure and how they are made.
- Class I and II have been well-studied, but there's less information about the other three classes, including a newly discovered class III family.
- Andalusicin, a member of this class, contains a unique structure with two methyl groups that have not been seen in other class III lanthipeptides, and it exhibits bioactivity against Gram-positive bacteria, influenced by its methylation.
PGLYRP1/Tag-7/PGRP-S is one of mammalian peptidoglycan recognition proteins (PGRPs). Here, we demonstrate that human recombinant PGLYRP1/Tag-7/PGRP-S potentiates the response of murine macrophage-like ANA-1 cells and human macrophages to facultative intracellular pathogen . PGLYRP1/Tag-7/PGRP-S binds to the surface of and other bacterial cells but has no effect on their growth in culture.
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