Publications by authors named "Darwin Tsinajinne"
Article Synopsis
- Population genetic screening for preventable adult-onset hereditary conditions may enhance disease management but often yields uninformative results, with many individuals not at greater risk for illness.
- A study at the University of Washington examined responses from 1352 patients who received these uninformative results, focusing on their perceived changes in health risk and behavior.
- Findings indicated low psychosocial harms from the screening, with only a small percentage believing their disease risk had changed or planning to alter their healthcare behaviors, highlighting the need for more research on the long-term impact of such screening results.
Background: Population screening for genetic risk of adult-onset preventable conditions has been proposed as an attractive public health intervention. Screening unselected individuals can identify many individuals who will not be identified through current genetic testing guidelines.
Methods: We sought to evaluate enrollment in and diagnostic yield of population genetic screening in a resource-limited setting among a diverse population.