Concomitant and protective immunity in mice exposed to repeated infections with Echinostoma malayanum.

Concomitant immunity and its consequence against infection play roles in regulating worm burdens in helminthiasis. Under natural conditions, this immunity is generated by exposure to repeated low dose or trickle infection. In this study, concomitant immunity was induced in mice exposed repeatedly to infection with Echinostoma malayanum and its protective effect on a challenge infection evaluated.

Immunohistochemical analyses of survivin and heat shock protein 90 expression in patients with oral lichen planus.

Background: Survivin is an inhibitor of apoptosis protein. Heat shock protein 90 (Hsp90) is a molecular chaperone that is involved in protein folding and maturation. Alterations in the expression of survivin and Hsp90 have been reported in several chronic inflammatory diseases.

Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis.

Oral lichen planus (OLP) is a chronic inflammatory disease, which has been clinically associated with development to oral cancer. A double immunofluorescence labeling study found that 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) accumulated in oral epithelium in OLP and oral squamous cell carcinoma (OSCC) biopsy specimens, whereas little or no immunoreactivity was observed in normal oral mucosa. Colocalization of 8-nitroguanine and inducible nitric oxide synthase (iNOS) was found in oral epithelium of OLP and OSCC.

Nasopharyngeal tuberculosis: manifestations between 1991 and 2000.

Objectives/hypothesis: To present the clinical manifestation of nasopharyngeal tuberculosis.

Study Design: Clinical analysis of 23 patients with pathologically confirmed nasopharyngeal tuberculosis was carried out retrospectively.

Setting: Srinagarind Hospital, Khon Kaen University.

Pleuropulmonary blastoma in a child presenting with spontaneous pneumothorax.

The authors described a 27-month-old boy with the diagnosis of pleuropulmonary blastoma who presented with spontaneous pneumothorax. The child was admitted to our hospital with the chief complaint of respiratory distress for 8 months. Initial chest X-ray revealed tension pneumothorax on the right side.