Publications by authors named "Darshan Parikh"

The challenges of developing good quality low dose minitablets was assessed by systematically studying the effects of ibuprofen (IBU, a model compound) particle sizes (6-58 µm D) and concentrations (0.1-3 %w/w), roller compaction forces (3-7 kN/cm), and the minitablet sizes (1.2, 1.

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This study describes trends in surgical versus endovascular interventions for treatment of chronic superficial venous disease (SVD) in the Medicare population. Medicare Part B data from 2010 to 2018 were obtained. Claims for SVD treatment were identified using Healthcare Common Procedure Coding System codes.

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Introduction: Surgery remains main treatment of choice for thyroid nodule for diagnosis and treatment. Conventional thyroid surgery gives scar in the neck so many young patients particularly unmarried females demand thyroid surgery without visible scar in the neck for cosmetic reason. Extra cervical approaches have continued to evolve with an increasing body of research (Sarda AK, Bal S, Kapoor MM (1989) Near-total thyroidectomy for carcinoma of thyroid.

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Article Synopsis
  • Cervical spine injuries (CSI) are uncommon in kids, leading to excessive imaging to avoid missed diagnoses. This study aimed to evaluate if a single lateral cervical radiograph (LAT) could effectively identify CSIs compared to multiple views and other imaging methods.* -
  • Data from 3,735 radiographs showed that LAT could visualize all bony CSIs, with half of the abnormal findings on initial radiographs being false positives upon further imaging like CT and MRI.* -
  • The findings suggest that using a single LAT is as effective as multiple views for detecting bony CSIs, and while LAT missed some ligamentous injuries, MRI should be preferred for further evaluation in such cases to minimize unnecessary radiation exposure.*
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Pediatric and adolescent patients frequently are seen in the outpatient practices of general orthopaedic surgeons. Orthopaedic conditions may be a challenge to diagnose and manage in pediatric and adolescent patients. To avoid complications, general orthopaedic surgeons should understand current diagnostic techniques, evaluation methods, and treatment options for orthopaedic spine, hip, and lower extremity conditions that are common in pediatric and adolescent patients.

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Feasibility of developing a transdermal drug delivery of fluoxetine has been investigated. Permeation studies of fluoxetine across human cadaver skin were carried out using Franz diffusion cells. The receptor phase consisted of pH 7.

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