Publications by authors named "Darshan N Shah"

Creutzfeldt Jakob Disease (CJD) is a rapidly progressive and fatal neurodegenerative disease that is uncommonly accompanied with seizures. In this case report, we describe a 63-year-old male patient who presented with a 3-week history of visual disturbances and clonic movement of his left arm. Additionally, the patient was reported to have developed erratic behaviors along with insomnia during this period.

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Article Synopsis
  • A regional network of ten hospitals implemented tenecteplase as the standard treatment for stroke in 2019, believing it would improve workflow and offer similar clinical outcomes compared to the traditional alteplase treatment.
  • A study comparing 234 tenecteplase patients to 354 alteplase patients found that tenecteplase significantly reduced door-to-needle times and door-in-door-out times, while showing noninferior favorable and lower unfavorable outcomes.
  • Overall, tenecteplase demonstrated a greater net benefit and lower average treatment costs compared to alteplase, suggesting it could be a more efficient option for stroke care.
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Introduction: Primary cervical and oromandibular dystonia (CD and OMD, respectively) are well-recognized movement disorders, often treated with botulinum toxin (BTx). In contrast, dystonia related to acute brain injuries is not well delineated. Our objective was to define in neurocritically ill patients the clinical characteristics of CD and OMD and to investigate the safety of BTx.

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