Faster in and faster out: accelerating insulin absorption and action by insulin infusion site warming.

Objective: This study was undertaken to investigate the effect of an insulin infusion site warming device, the InsuPatch(40)(™) (IP(40)) (InsuLine Medical Ltd., Petach-Tikvah, Israel), on insulin aspart pharmacodynamics (PD) and pharmacokinetics (PK) in adolescents with type 1 diabetes.

Subjects And Methods: Seventeen subjects with type 1 diabetes (age, 15±1 years; hemoglobin A1c, 7.