Publications by authors named "Darren Karl Griffin"
Article Synopsis
- The study aimed to identify factors affecting the proportion of chromosomally balanced embryos in couples with structural rearrangements and to explore if there is an interchromosomal effect (ICE).
- Researchers analyzed preimplantation genetic testing data from 300 couples involving over 1,800 embryos and found that 23.8% were normal/balanced and euploid.
- Key findings indicated that complex translocations and female age (≥35) negatively impacted the chance of having transferable embryos, but there was minimal evidence supporting an ICE, leading to recommendations for improved genetic assessment for these couples.
Although Rallidae is the most diverse family within Gruiformes, there is little information concerning the karyotype of the species in this group. In fact, Gallinula melanops, a species of Rallidae found in Brazil, is among the few species studied cytogenetically, but only with conventional staining and repetitive DNA mapping, showing 2n=80. Thus, in order to understand the karyotypic evolution and phylogeny of this group, the present study aimed to analyze the karyotype of G.
View Article and Find Full Text PDFis a small Neotropical parrot (Psittaciformes: Arini Tribe) from subtropical and temperate regions of South America. It has a diploid chromosome number 2 = 48, different from other members of the Arini Tribe that have usually 70 chromosomes. The species has the lowest 2 within the Arini Tribe.
View Article and Find Full Text PDFOrganisation of chromosome territories in interphase nuclei has been studied in many systems and positional alterations have been associated with disease phenotypes (e.g. laminopathies, cancer) in somatic cells.
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