High-throughput antibody screening with high-quality factor nanophotonics and bioprinting.

Empirical investigation of the quintillion-scale, functionally diverse antibody repertoires that can be generated synthetically or naturally is critical for identifying potential biotherapeutic leads, yet remains burdensome. We present high-throughput nanophotonics- and bioprinter-enabled screening (HT-NaBS), a multiplexed assay for large-scale, sample-efficient, and rapid characterization of antibody libraries. Our platform is built upon independently addressable pixelated nanoantennas exhibiting wavelength-scale mode volumes, high-quality factors (high-Q) exceeding 5000, and pattern densities exceeding one million sensors per square centimeter.

The Dopamine Assisted Synthesis of MoO/Carbon Electrodes With Enhanced Capacitance in Aqueous Electrolyte.

A capacitance increase phenomenon is observed for MoO electrodes synthesized a sol-gel process in the presence of dopamine hydrochloride (Dopa HCl) as compared to α-MoO electrodes in 5M ZnCl aqueous electrolyte. The synthesis approach is based on a hydrogen peroxide-initiated sol-gel reaction to which the Dopa HCl is added. The powder precursor (Dopa)MoO, is isolated from the metastable gel using freeze-drying.