Publications by authors named "Darrah Spies"
Article Synopsis
- - The study aimed to validate a biomarker signature for chronic pain management, using measures called peak alpha frequency (PAF) and corticomotor excitability (CME), in a model induced by nerve growth factor injections in the jaw muscle.
- - A total of 150 participants experienced pain for up to 4 weeks post-injection, with EEG and TMS used to assess PAF and CME; machine learning models were developed to predict pain sensitivity based on these measures.
- - The analysis showed that logistic regression was extremely effective, achieving perfect classification in training and strong performance in testing, indicating the PAF/CME biomarker signature has great promise for clinical applications in pain assessment.
