Publications by authors named "Dariusz Korzen"

Article Synopsis
  • The study aimed to evaluate classic risk factors in patients with heart failure and their correlation with the activity of specific genes.
  • It involved 150 patients, including those with heart failure due to coronary artery disease, with the most common risk factors being hypertension and obesity.
  • Higher gene activity was linked to risk factors like obesity and smoking, indicating their roles in the progression of heart failure during myocardial ischemia, emphasizing the need for education on healthy lifestyle choices.
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The most common cause of heart failure (HF) is coronary artery disease (CAD). The aim of this study was to evaluate the transcriptional activity of the () and () genes in a study group of patients with HF due to CAD and in the control group, as well as assess the transcriptional activity of the examined genes, taking into account the number of affected coronary arteries and the severity of heart failure. The study group consisted of a total of 150 (100%) patients.

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Background: Heart failure (HF) is a major cause of mortality in developed countries. Its formation is associated with a change in the transcriptional activity of many genes. The aim of the study was to select, from the group of genes related to coronary atherosclerosis and heart failure, genes differentiating patients with coronary heart disease and heart failure on the basis of myocardial ischemia from healthy people, and then genes differentiating patients with various stages of heart failure.

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