Publications by authors named "Darius Kurt"
Light sheet fluorescence microscopy (LSFM) is a transformative imaging method that enables the visualization of non-dissected specimen in real-time 3D. Optical clearing of tissues is essential for LSFM, typically employing toxic solvents. Here, we test the applicability of a non-hazardous alternative, ethyl cinnamate (ECi).
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- Image-based detection of intralesional fat in liver lesions is important for diagnosing hepatocellular carcinoma (HCC) and correlates with better prognosis, prompting this study to examine the link between fat content and tumor grade in steatotic HCCs.
- The study analyzed 57 patients with steatotic HCC, finding that higher intralesional fat content in well-differentiated (G1) tumors compared to less-differentiated (G2 and G3) tumors, indicating that fat quantification could help differentiate tumor grades.
- The use of MRI proton density fat fraction (PDFF) mapping proved effective in distinguishing between different grades of HCC, suggesting its potential role in enhancing precision medicine for tumor