Precise kilobase-scale genomic insertions in mammalian cells using PASTE.

Programmable gene integration technologies are an emerging modality with exciting applications in both basic research and therapeutic development. Programmable addition via site-specific targeting elements (PASTE) is a programmable gene integration approach for precise and efficient programmable integration of large DNA sequences into the genome. PASTE offers improved editing efficiency, purity and programmability compared with previous methods for long insertions into the mammalian genome.

Sensor-Aided V2X Beam Tracking for Connected Automated Driving: Distributed Architecture and Processing Algorithms.

This paper focuses on ultra-reliable low-latency Vehicle-to-Anything (V2X) communications able to meet the extreme requirements of high Levels of Automation (LoA) use cases. We introduce a system architecture and processing algorithms for the alignment of highly collimated V2X beams based either on millimeter-Wave (mmW) or Free-Space Optics (FSO). Beam-based V2X communications mainly suffer from blockage and pointing misalignment issues.