Publications by authors named "Dario Di Maio"
The urgent need to meet the stringent regulation requirements on sub-23 nm particles emissions is pushing the interest towards efficient strategies for their reduction, involving different propulsive technologies, including the Natural Gas engines. Although considered as particulate matter-free, the growing diffusion of Natural Gas Heavy-Duty engines as a key element in the low-term towards decarbonization, requires their compliance with upcoming regulations. The use of particulate filters, in combination with the Three-Way Catalyst (TWC), could represent a promising and viable solution to achieve high conversion of gas-phase criteria pollutants and high particles filtration efficiency.
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- The study focuses on creating and validating a risk score to predict the likelihood of needing to switch from radial artery access to femoral access in patients with acute coronary syndromes (ACS) undergoing invasive procedures.
- The MATRIX score, developed from a sample of over 4,000 ACS patients, incorporates factors like age, smoking history, and renal failure, showing a decent ability to predict crossover risk.
- By providing a standardised tool, the MATRIX score aims to help medical professionals anticipate complications during transradial procedures, which could lead to better patient outcomes.
Article Synopsis
- Stroke is the leading global cause of disability and death, with about 20% of patients experiencing recurrent vascular events like stroke or TIA within three months after an initial event.
- Antiplatelet therapy is crucial for reducing the risk of these recurrent events, particularly in cases not related to heart issues (non-cardioembolic).
- This review examines the effectiveness of commonly used antiplatelet medications—aspirin, clopidogrel, and ticagrelor—as outlined in practice guidelines for stroke and TIA management.
Article Synopsis
- This study aimed to evaluate the effects of access-site crossover in patients with acute coronary syndrome receiving treatment through either radial or femoral access methods.
- In the MATRIX-Access trial involving over 8,400 patients, it was found that crossover from one access site to another was relatively low but notably had different outcomes depending on the direction of the crossover.
- Specifically, radial access crossover did not show significantly higher risks for major cardiovascular events compared to successful access, while femoral crossover was linked to increased risks for both major adverse cardiovascular events and net adverse clinical events.
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- This study investigates the impact of in-hospital hemoglobin drop on patients with acute coronary syndrome (ACS), focusing on how this drop affects patient outcomes, regardless of overt bleeding.
- It categorizes hemoglobin drop as minimal, minor, or major and examines its correlation with 1-year mortality in patients who experienced bleeding compared to those who did not.
- The findings reveal that even without overt bleeding, significant hemoglobin drops are associated with increased mortality, suggesting that hemoglobin levels could be an important prognostic factor in ACS management.
Functionally significant coronary lesions identification is necessary for appropriate revascularization. This review aims to provide an overview of the available options for coronary stenosis physiologic evaluation with a focus on the latest developments in the field.
View Article and Find Full Text PDFBackground: The twelve‑lead electrocardiogram (ECG) has become an essential tool for the diagnosis, risk stratification, and management of patients with acute coronary syndromes (ACS). However, several areas of residual controversies or gaps in evidence exist. Among them, P-wave abnormalities identifying atrial ischemia/infarction are largely neglected in clinical practice, and their diagnostic and prognostic implications remain elusive; the value of ECG to identify the culprit lesion has been investigated, but validated criteria indicating the presence of coronary occlusion in patients without ST-elevation are lacking; finally, which criteria among the multiple proposed, better define pathological Q-waves or success of revascularisation deserve further investigations.
View Article and Find Full Text PDFBackground: Dual antiplatelet therapy (DAPT) with aspirin and ticagrelor is recommended for at least 12 months in patients after an acute coronary syndrome (ACS). However, its underuse and premature discontinuation are common in clinical practice. We aimed to investigate the impact of a dedicated follow-up strategy with clinical visits and counselling on adherence levels to ticagrelor in patients after ACS.
View Article and Find Full Text PDFThe majority of currently published dispersion protocols of carbon nanotubes rely on techniques that are not scalable to an industrial level. This work shows how to obtain polymer nanocomposites with good mechanical characteristics using multi-walled carbon nanotubes epoxy resins obtained by mechanical mixing only. The mechanical dispersion method illustrated in this work is easily scalable to industrial level.
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