Publications by authors named "Darin A Trier"
Infect Immun
December 2008
Article Synopsis
- - Platelets (PLTs) play a role in fighting infections by releasing microbicidal proteins (PMPs) and kinocidins (PKs) against Staphylococcus aureus, particularly when PLT-to-bacteria ratios exceed 10:1, showing significant effectiveness against both susceptible and resistant strains.
- - Inhibitors targeting various PLT receptors, like P2X and P2Y, reduce the release of PMPs and PKs, compromising PLT's antimicrobial activity, but other pathways related to thromboxane A(2) and cyclooxygenase's function do not affect the anti-staph responses.
- - The mechanism behind PLT's anti-S. aureus action includes a critical
