Interventions for preventing back pain among office workers - a systematic review and network meta-analysis.

Objective: Back pain is common in the working population. This systematic review with network meta-analysis (NMA) aimed to compare the effects of interventions for preventing back pain among office workers.

Methods: We searched eight databases and additional sources up to March 2021.

Work-related interventions for preventing back pain-protocol for a systematic review and network meta-analysis.

Background: Back pain is a widespread health problem that accounts for substantial disability and high costs. The workplace is considered to critically affect the occurrence and persistence of back pain and therefore offers an important opportunity for preventive interventions. Various work-related intervention strategies including both single- and multicomponent interventions have been developed and evaluated so far.

Acute exercise impacts AhR and PD-1 levels of CD8 T-cells-Exploratory results from a randomized cross-over trial comparing endurance versus resistance exercise.

Purpose: The programmed cell death protein 1 (PD-1) has become a promising target in cancer immunotherapy. PD-1 expression of CD8 T-cells may be increased via the exploitation of aryl hydrocarbon receptor (AhR) signaling with kynurenine (KYN) as a ligand. Since exercise affects KYN metabolism, we exploratory investigated the influence of acute exercise bouts on AhR and PD-1 levels of CD8 T-cells.