Nucl Instrum Methods Phys Res A
November 2022
Owing to the favorable depth-dose distribution and the radiobiological properties of heavy ion radiation, ion beam therapy shows an improved success/toxicity ratio compared to conventional radiotherapy. The sharp dose gradients and very high doses in the Bragg peak region, which represent the larger physical advantage of ion beam therapy, make it also extremely sensitive to range uncertainties. The use of -radioactive ion beams would be ideal for simultaneous treatment and accurate online range monitoring through PET imaging.
View Article and Find Full Text PDFSeveral techniques are under development for image-guidance in particle therapy. Positron (β) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human body. In heavy ion therapy, a major part of the PET signals is produced by β-emitters generated projectile fragmentation.
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