Publications by authors named "Daria Feldmann"

Article Synopsis
  • The study investigates the link between elevated C-reactive protein (CRP) levels and cardiovascular risk in systemic sclerosis (SSc) patients, focusing on how CRP positivity may indicate chronic inflammation and increased atherosclerosis risk compared to those without CRP elevation.
  • Researchers categorized 65 SSc patients into CRP+ (with prolonged elevated CRP levels) and CRP- (without elevated levels) to study associations with cardiovascular health, using methods like blood tests and carotid ultrasound to assess arteriosclerotic burden.
  • The goal is to better understand which cardiovascular and SSc-specific factors can differentiate patients with high CRP levels from those without, employing advanced classification techniques like random forest modeling
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Objectives: About 25% of patients with systemic sclerosis (SSc) have elevated C-reactive protein (CRP) levels. Specific causes of CRP elevation are unknown so far. We aimed to investigate whether inflammatory arthritis is associated with CRP elevation.

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Background/purpose: Elevated levels of C-reactive protein (CRP) in systemic sclerosis (SSc) have been linked to early inflammatory stages of the disease. This study has been designed to investigate CRP levels longitudinally in a cohort of SSc patients and to correlate these findings with comorbidities and disease characteristics.

Methods: In this retrospective study, patients with SSc treated at the outpatient clinic of the Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, were analyzed.

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