Publications by authors named "Darcy Davies"
Additions to the OPTN waiting list decreased in 2003 for all organs except kidney. On November 30, 2004 there were 95,598 registrations on the combined UNOS waiting list. Of these, 67% were awaiting kidney transplantation and 18% were awaiting liver transplantation.
View Article and Find Full Text PDFOn February 27, 2002 the United Network for Organ Sharing OPTN implemented a revised system for the allocation of deceased donor livers. When compared to an earlier era, preliminary results for pediatric patients indicate that transplant rates increased for the sickest patients at listing (Status 1) and that death rates decreased for the sickest patients at listing. The PELD score was initially validated with the same data with which it was created and had an AUC ROC of 0.
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- The study focuses on short-term survival rates following lung transplantation (LT) for patients with sarcoidosis, revealing that around 83% survive past 30 days compared to 91% for other conditions.
- Factors like requiring mechanical ventilation, being treated in an ICU, and donor age were linked to higher mortality rates, while African American patients faced nearly a 50% increased risk of death post-transplant.
- Despite these differences, once controlling for various factors, survival rates for sarcoidosis patients were similar to those undergoing LT for other diseases, with graft failure being the leading cause of death for them.
Objectives: To identify factors associated with mortality in patients with sarcoidosis listed for lung transplantation, and to create a model for predicting intermediate-term mortality in these individuals.
Design: Retrospective cohort study of patients with sarcoidosis listed for lung transplant in the United States between 1995 and 2000. After identifying important risk factors for death, we developed a mortality prediction model based on an inception cohort of 75% of the subjects.
Although it is well established that acute rejection is one of the major risk factors for chronic graft loss following kidney transplantation, its effect on long-term graft survival following simultaneous kidney-pancreas transplants (SKPTs) is less well known. We analyzed a large cohort of SKPTs and cadaver kidney transplants reported to the United Network for Organ Sharing database during 1988-97, to determine the impact of acute rejection episodes on long-term kidney and pancreas graft survival. Only patients whose kidney and pancreas grafts had survived for at least 1 year were included.
View Article and Find Full Text PDFStudy Objectives: To describe the population of patients with sarcoidosis listed for orthotopic lung transplantation (OLT) in the United States, and to determine outcomes for these subjects relative to persons awaiting OLT for idiopathic pulmonary fibrosis (IPF).
Design: Retrospective analysis of the United Network for Organ Sharing transplant database over the period between January 1995 and December 2000.
Patients: All patients listed for OLT with an underlying diagnosis of either sarcoidosis or IPF.