Cochlear Implantation in children with CHARGE syndrome.

Unlabelled: CHARGE syndrome is a rare congenital condition that manifests with anomalies of coloboma, heart defects, choanal atresia, mental retardation, genitourinary and ear anomalies that can affect almost any part of the auditory pathway. In those patients with a significant sensorineural hearing loss, cochlear implantation has become a potential therapeutic option.

Methods: Chart review of three cases from the Southern Cochlear Implant Programme.

Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph.

Objective: To measure dexamethasone concentrations in the plasma and perilymph of the human ear after intravenous (IV) and intratympanic (IT) administration and to compare these with previous studies with methylprednisolone.

Methods: Patients were administered dexamethasone by the IT or IV routes approximately 0.5 to 2 hours before cochlear implantation.

Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph.

Objective: To compare methylprednisolone concentrations in the perilymph of the human ear and in plasma after intratympanic (IT) or intravenous (IV) administration.

Methods: Methylprednisolone concentrations in the perilymph of patients during cochlear implantation were compared after 3 dosing strategies of methylprednisolone solution for injection (40 mg/ml): 1) IT administration of up to 40 mg was injected into the middle ear through the external auditory canal via a 27-gauge needle passed through a small anterosuperior myringotomy; 2) IV administration of 1 mg/kg was given as a single injection over 30 seconds; 3) IV administration of 10 mg/kg was infused over 30 minutes. Perilymph (single sample, approximately 20 microL) was sampled using a needle passed through the round window membrane, from 0.

Preservation of the superficial lobe for deep-lobe parotid tumors: a better aesthetic outcome.

Deep-lobe parotid tumors are relatively uncommon. Most of these tumors present as external masses. They can also present in the oral cavity or oropharynx.

Modified submandibular sialoadenectomy.

Submandibular sialoadenectomy is a common head and neck procedure. Indications include the presence of benign and malignant tumors and inflammatory disease with or without intraglandular sialolithiasis. The standard technique involves a variably sized incision.

Extra-abdominal fibromatosis: a case report.

Head and neck fibromatosis is a rare disease with a variable clinical picture. We report the case of a 40-year-old woman who had a 1-week history of a painless mass overlying her right neck. Histology confirmed a diagnosis of extra-abdominal fibromatosis.