Antibacterial and Mechanical Properties of Pit and Fissure Sealants Containing Zinc Oxide and Calcium Fluoride Nanoparticles.

Context: Pit and fissure sealants (PFSs) are the most effective preventive materials in dentistry. Secondary caries around the sealed pits and fissures at the material-tooth interface and the wear of the material remains the common problems. To address these problems, efforts have been made by incorporating zinc oxide (ZnO) and calcium fluoride (CaF) nanoparticles (NPs) into the sealants to develop caries-inhibiting and stress-bearing sealants.