Publications by authors named "Daphne Weikart"

Article Synopsis
  • - This study investigates whether cocoa and its polyphenol-rich fractions have anti-inflammatory effects in a mouse model of acute colonic inflammation induced by dextran sulfate sodium (DSS).
  • - Male mice received dietary cocoa treatments for two weeks before and during DSS-induced inflammation, but cocoa did not prevent weight loss or reduced colon size, although it improved spleen enlargement.
  • - Overall, the findings indicate that cocoa and cocoa polyphenols are not effective in reducing acute colonic inflammation, as evidenced by inflammatory markers and the similarity of treated mice to the control group subjected to DSS.
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Obesity causes inflammation which may lead to development of co-morbidities like cardiovascular diseases. Cocoa is a popular food ingredient that has been shown to mitigate obesity and inflammation in preclinical models. Cocoa typically undergoes fermentation and roasting prior to consumption, which can affect the polyphenol content in cocoa.

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Sub-optimal diet and physical activity (PA) levels have been associated with increased risk of cardiovascular disease (CVD) mortality. The relationship between pre-cancer diagnosis diet quality and PA level on CVD mortality risk in cancer survivors is unclear. We examined the association between pre-cancer diagnosis diet quality and leisure-time PA and their interaction on CVD mortality in cancer survivors.

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