Synopsis of recent research by authors named "Daphne Nikles"
- Daphne Nikles' research primarily focuses on the interactions and mechanisms of prion proteins and their receptors, particularly the 37-kDa/67-kDa laminin receptor, in both prion disorders and cancer.
- Her studies demonstrate innovative therapeutic strategies using small interfering RNAs and lentiviral vectors to inhibit the effects of prion diseases, significantly reducing harmful receptor levels in infected models.
- Nikles provides insights into the role of ABC transporters in health and disease, emphasizing the importance of their degradation processes in cellular function, which contributes to understanding various pathologies, including transmissible spongiform encephalopathies (TSEs).
