Publications by authors named "Daphne Garcia-Vega"
Article Synopsis
- - Primary congenital glaucoma (PCG) is a significant cause of vision loss in children, characterized by high intraocular pressure leading to optic nerve damage and various symptoms like excessive tearing and light sensitivity.
- - Diagnosis and treatment are crucial for preserving vision in affected individuals, as PCG can manifest in diverse ways among patients.
- - The study focuses on Mexican patients with TEK-related PCG, identifying the TEK gene as a key factor in the disease and reporting 10 new mutations that contribute to its development.
Idiopathic orbital inflammation (IOI) is a diagnosis of exclusion, but the exclusion of other inflammatory diseases of the orbit is broad and relies on clinician experience, response to corticosteroid, or biopsy. This study aimed to investigate the presence of granulomatosis with polyangiitis (GPA) in patients initially diagnosed as IOI and describe its clinicopathological features, ANCA status, treatment, and outcome. We performed a retrospective case series study of children diagnosed with limited GPA (L-GPA) in patients with IOI.
View Article and Find Full Text PDFCirculating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors.
PLoS One
July 2020
miRNAs regulate post-transcriptional gene expression in metazoans, and thus are involved in many fundamental cellular biological processes. Extracellular miRNAs are also found in most human biofluids including plasma. These circulating miRNAs constitute a long distance inter cellular communication system and are potentially useful biomarkers.
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