Evolutionary game analysis of indoor radon mitigation with local government involvement.

Radon is the second leading risk factor for lung cancer after smoking. As a public policy, radon mitigation not only involves radon control technology or its cost-benefit analysis, but also includes the decision-making process of local governments. In this study, the evolutionary game theory was used to analyse the interaction between local governments and residents based on the subsidy of the central government.

Hsa_circ_0001535 Regulates Colorectal Cancer Progression via the miR-433-3p/RBPJ Axis.

A large number of studies have shown that circular RNAs (circRNAs) are of great significance in the occurrence and development of colorectal cancer (CRC). The purpose of this study was to explore the mechanism of circ_0001535 in CRC. The expressions of circ_0001535, miR-433-3p and recombination signal-binding protein Jκ (RBPJ) mRNA and protein in CRC tissues and cells were detected by quantitative real-time polymerase chain reaction (qRT-PCR) or western blot.

Genetic Variants of the Gene and Susceptibility of Rectal Cancer.

Background: Rectal cancer (RC) has been documented to be a highly invasive malignant neoplasm worldwide. Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine involved in cell-mediated immunity, immunoregulation, inflammation. In vitro and in vivo studies have identified that MIF was involved in the carcinogenesis and progression of RC.

Preoperative assessment of complicated appendicitis through stress reaction and clinical manifestations.

This study assessed the severity of the disease through the preoperative clinical manifestations and inflammatory reaction indicators of acute appendicitis, and established a score table to predict complicated appendicitis (CA).The clinical data of 238 patients with acute appendicitis in our hospital were retrospectively analyzed, which included 18 patients with acute simple appendicitis (7.6%), 170 patients with acute purulent appendicitis (72.

miR‑329‑3p regulates neural stem cell proliferation by targeting E2F1.

Neural stem cells (NSCs) are a class of self‑renewing and undifferentiated progenitor cells that retain the ability to differentiate to neurons, astrocytes and oligodendrocytes. MicroRNAs (miRNAs) are small noncoding RNAs that serve crucial roles in regulating a number of cellular processes, including cell proliferation, differentiation and apoptosis. Our previous GeneChip data indicated that the expression of miR‑329‑3p was increased in neurons compared with NSCs.

Lymph node ratio is an independent prognostic factor in gastric cancer after curative resection (R0) regardless of the examined number of lymph nodes.

Objectives: The purpose of this study was to evaluate the outcome of the ratio between metastatic and examined lymph nodes (N ratio) in gastric cancer patients with <15 examined lymph nodes after curative resection.

Methods: A retrospective study of 710 patients who underwent radical gastrectomy (R0) for gastric cancer from January 1980 to December 2000 was analyzed statistically to identify the N ratio. Patients with <15 examined lymph nodes (group 1, n=327) and those with ≥15 examined lymph nodes (group 2, n=383) were analyzed separately.