Chemistry Combining Elemental Profile, Stable Isotopic Ratios, and Chemometrics for Fine Classification of a Chinese Herb Licorice ( Fisch.) from 37 Producing Area.

A method based on elemental fingerprint, stable isotopic analysis and combined with chemometrics was proposed to trace the geographical origins of Licorice ( Fisch) from 37 producing areas. For elemental fingerprint, the levels of 15 elements, including Ca, Cu, Mg, Pb, Zn, Sr, Mn, Se, Cd, Fe, Na, Al, Cr, Co, and K, were analyzed by inductively coupled plasma atomic emission spectrometry (ICP-AES). Three stable isotopes, including C, N, and O, were measured using an isotope-ratio mass spectrometer (IRMS).

Synthesis and Bioactivities of Novel Galactoside Derivatives Containing 1,3,4-Thiadiazole Moiety.

A series of novel galactoside derivatives containing 1,3,4-thiadiazole moiety were synthesized, and the structure of them was verified by spectroscopy of NMR and HRMS, and antifungal and antibacterial activities of them were screened. The results showed that the newly synthesized compounds had good antifungal activities. Among them, Ⅲ16, Ⅲ17, and Ⅲ19 exhibited satisfactory activities against , with EC values of 5.

Synthesis and Bioactivities of Novel 1,3,4-Thiadiazole Derivatives of Glucosides.

A series of novel 1,3,4-thiadiazole derivatives of glucosides were synthesized by the starting materials -glucose and 5-amino-1,3,4-thiadiazole-2-thiol in good yields with employing a convergent synthetic route. The results of bioactivities showed that some of the target compounds exhibited good antifungal activities. Especially, compounds showed higher bioactivities against (), with the EC values of 3.

Chemometric Analysis of Elemental Fingerprints for GE Authentication of Multiple Geographical Origins.

The feasibility of combining elemental fingerprints and chemical pattern recognition methods for authentication of the geographical origins of a Chinese herb, BI. (GE), was studied in this paper. A total of 210 GE samples were collected from 7 different producing areas.

ZnCdSe-CdTe quantum dots: A "turn-off" fluorescent probe for the detection of multiple adulterants in an herbal honey.

To enhance the power of untargeted detection, a "turn-off" fluorescent probe with double quantum dots (QDs) was developed and coupled with chemometrics for rapid detection of multiple adulterants in an herbal (Rhus chinensis Mill., RCM) honey. The double water-soluble ZnCdSe-CdTe QDs have two separate and strong fluorescent peaks, which can be quenched by honey and extraneous adulterants with varying degrees.