Case report: The outcomes of neoadjuvant immunotherapy combined with chemotherapy in pulmonary sarcomatoid carcinoma: case series and literature review.

Background: Pulmonary sarcomatoid carcinoma (PSC) is a highly aggressive malignancy with a significant risk of recurrence even after surgical intervention, leading to a dismal prognosis. In recent years, perioperative immunotherapy has demonstrated promising results in resectable non-small cell lung cancer (NSCLC). However, there is a lack of studies reporting the efficacy of perioperative immunotherapy in PSC.

Nomogram model for predicting long-term survival in esophageal cancer patients with metastasis after treatment: a SEER-based study.

Background: There is a large variance in the long-term survival of esophageal cancer (EC) patients with metastasis after treatment. This study was designed to analyze long-term survival of metastatic EC patients after surgery, radiotherapy and chemotherapy.

Methods: A retrospective cohort of EC patients with metastasis received surgery, radiotherapy and chemotherapy from 2004 to 2015 was obtained from the Surveillance, Epidemiology and End Results (SEER) database.

Characteristics of a heavy metal resistant heterotrophic nitrification-aerobic denitrification bacterium isolated from municipal activated sludge.

The heterotrophic nitrification-aerobic denitrification (HNAD) is a new biological denitrification technology, the present study isolated a new HNAD strain named Cupriavidus metallidurans TX6 with heavy metal resistance. The gene expression, electron transport, enzyme activity and nitrogen removal property of strain TX6 were studied with different influencing factors. Strain TX6 has five nitrogen metabolism pathways (NH → NHOH → NO → NO → NH → GOGAT/GDH; NH-N → NHOH → NO → NO → N; NH → NHOH → NO → NO → NO; NO → NO → NH → GOGAT/GDH; NO→ NO → NH → GOGAT/GDH).

Ipsilateral synchronous papillary renal neoplasm with reverse polarity and urothelial carcinoma in a renal transplant recipient: a rare case report with molecular analysis and literature review.

Background: Renal transplant recipients (RTRs) have a 3- to 5-fold higher risk of developing malignant tumors than the general population, with new malignant tumors after transplantation considered to be the leading cause of death in RTRs. In pathological practice, it is rare for neoplasms with different histology to be located in the same organ. We report the first case of a synchronous papillary renal neoplasm with reverse polarity (PRNRP) and urothelial carcinoma (UC) in the ipsilateral kidney in an RTR.

Co-gasification of rural solid waste and biomass in rural areas: Simulation and plant-scale process.

Co-gasification technology is considered to be one of the most potential technologies for solid waste treatment, and the co-gasification treatment of rural solid waste (RSW) and biomass can effectively promote waste reduction and resource utilization. In the present study, the co-gasification of RSW and biomass in an updraft fixed bed gasifier was simulated using the Aspen Plus software, where the simulation results were validated via plant-scale experiments. In this scenario, the impacts of biomass source (i.

A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.

Chronic liver diseases (CLD) frequently derive from hepatic steatosis, inflammation and fibrosis, and become a leading inducement of cirrhosis and hepatocarcinoma. Molecular hydrogen (H) is an emerging wide-spectrum anti-inflammatory molecule which is able to improve hepatic inflammation and metabolic dysfunction, and holds obvious advantages in biosafety over traditional anti-CLD drugs, but existing H administration routes cannot realize the liver-targeted high-dose delivery of H, severely limiting its anti-CLD efficacy. In this work, a concept of local hydrogen capture and catalytic hydroxyl radical (·OH) hydrogenation is proposed for CLD treatment.

Thymus and lung mucosa-associated lymphoid tissue lymphoma with adenocarcinoma of the lung: a case report and literature review.

Background: Mucosa-associated lymphoid tissue (MALT) lymphoma is a common, low-grade, malignant B-cell lymphoma. However, simultaneous MALT lymphoma in the thymus and lung is extremely rare, and concomitant adenocarcinoma of the lung is even rarer. Herein, we report a rare case of a collision tumor in which MALT lymphoma was found in both the thymus and lung with Sjögren's syndrome (SS) and adenocarcinoma in the lung.

HuR affects chemoresistance of small cell lung cancer by regulating FGFRL1 expression.

Human antigen R (HuR), an RNA-binding protein, has been demonstrated to serve an oncogenic role in various types of cancer. Fibroblast growth factor receptor-like 1 (FGFRL1) has been shown to regulate small cell lung cancer (SCLC) chemoresistance. In the present study, the role of HuR in chemoresistance of SCLC, as well as its possible molecular mechanism involving FGFRL1, was explored by reverse transcription-quantitative PCR, western blotting, Cell Counting Kit-8 assay, flow cytometry and RNA immunoprecipitation.

Design and operation of a fixed-bed pyrolysis-gasification-combustion pilot plant for rural solid waste disposal.

This paper is to explore the use of rural solid waste (RSW) for pyrolysis-gasification-combustion in pilot plant scale aiming at sustainable management of rural waste in remote areas. Based on the experimental data obtained during pilot scale operation, the temperature in the furnace needs to be kept at least at 600 °C through analyzing the pyrolysis weight loss of the main combustibles in the RSW. Besides, the effects of the air supply method and ventilation rate on the pilot plant performance were explored.

Plexiform fibromyxoma: Case report and literature review.

Plexiform fibromyxoma (PF) is a rare mesenchymal neoplasm which can be misdiagnosed as the gastrointestinal stromal tumor. This tumor almost formed a lobulated intramural/submucosal mass in the gastric antrum and prepyloric area. It was considered as a benign tumor that exhibited no recurrence, metastasis, or tumor-related mortality.

A low-voltage pulse electrolysis method for the degradation of anthraquinone and azo dyes in chloride medium by anodic oxidation on Ti/IrO -RuO -SnO electrodes.

Wastewater produced by the textile industry containing azo dyes and anthraquinone dyes is significant source of pollution to the environment and is toxic for aquatic life. To overcome the high-energy cost of traditional electrochemical oxidation, a custom-built power supply device for the degradation of anthraquinone and azo dyes by low voltage of 15.0-20.

Evaluation of carboxymethylpullulan-AlCl as a coagulant for water treatment: A case study with kaolin.

A reduction in the use of aluminum (Al)-based flocculants in the treatment of drinking water is considered essential for human health reasons. In this study, a novel composite flocculant, made of carboxymethylpullulan-AlCl , is evaluated in a lab-scale, jar test system for the flocculation of kaolin. The results showed that the coagulation efficiency of carboxymethylpullulan-AlCl was more effective in reducing turbidity than the solo use of carboxymethylpullulan or AlCl .

Preferable phosphate removal by nano-La(III) hydroxides modified mesoporous rice husk biochars: Role of the host pore structure and point of zero charge.

Immobilizing La(OH) nanoparticles (NPs) to porous hosts has been widely applied to inhibiting their inherent aggregation as well as the subsequent low utilization efficiency of La. In this study, a series of rice husk biochars (RHBCs) with high mesoporous rates were prepared and the effects of host pore structure and point of zero charge (pH) on phosphate adsorption by La-modified RHBCs was particularly focused. Characterization results confirmed that La(OH) NPs were both confined in the pore channel and external surface of RHBCs.

Monolithic integration of InGaAs n-FETs and lasers on Ge substrate.

We report the first monolithic integration of InGaAs channel field-effect transistors with InGaAs/GaAs multiple quantum wells (MQWs) lasers on a common platform, achieving a milestone in the path of enabling low power and high speed opto-electronic integrated circuits (OEICs). The III-V layers used for realizing transistors and lasers were grown epitaxially on the Ge substrate using molecular beam epitaxy (MBE). A Si-CMOS compatible process was developed to realize InGaAs n-FETs with subthreshold swing SS of 93 mV/decade, I/I ratio of more than 4 orders of magnitude with very low off-state leakage current, and a peak effective mobility of more than 2000 cm/V·s.

Catalytic wet air oxidation of high concentration pharmaceutical wastewater.

In this study, we investigated the pretreatment of a high concentration pharmaceutical wastewater by catalytic wet air oxidation (CWAO) process. Different experiments were conducted to investigate the effects of the catalyst type, operating temperature, initial system pH, and oxygen partial pressure on the oxidation of the wastewater. Results show that the catalysts prepared by the co-precipitation method have better catalytic activity compared to others.

Photocatalytic pretreatment of oily wastewater from the restaurant by a vacuum ultraviolet/TiO2 system.

The present study aims at investigating the performance of a vacuum ultraviolet (VUV, 185 nm) and TiO(2) oxidation system for the pretreatment of oily wastewater from restaurant. The influence of irradiation time, pH, dissolved oxygen (DO), the dosage of TiO(2) and the initial chemical oxygen demand (COD) concentration on COD removal efficiency was ascertained and optimum process conditions for stable and effective operation were determined. Under the optimum conditions of irradiation 10 min, initial COD 3981 mg/L, TiO(2) 150 mg/L, pH 7.