Enhanced tumor targeting and penetration of fluorophores via iRGD peptide conjugation: a strategy for the precision targeting of lung cancer.

Background: Accurate real-time tumor delineation is essential for achieving curative resection (R0 resection) during non-small cell lung cancer (NSCLC) surgery. The unique characteristics of lung tissue structure significantly challenge the use of video-assisted thoracoscopic surgery in the identification of lung nodules. This difficulty often results in an inability to discern the margins of lung nodules, necessitating either an expansion of the resection scope, or a transition to open surgery.

Hydrogenated Boride-Assisted Gram-Scale Production of Platinum-Palladium Alloy Nanoparticles on Carbon Black for PEMFC Cathodes: A Study from a Practical Standpoint.

Platinum-palladium (PtPd) alloy catalysts with high durability are viable substituents to commercial Pt/C for proton exchange membrane fuel cells (PEMFCs). Herein, a facile approach for gram-scale preparation of PtPd alloy nanoparticles on carbon black is developed. The optimized PtPd/B-C catalyst shows a mass activity (MA) of 0.

FeO/NiO Interface for the Electrochemical Oxygen Evolution in Seawater and Domestic Sewage.

Hydrogen production from the electrolysis of seawater and domestic sewage is more attractive than that from pure water, especially in regions where freshwater resources are scarce. However, under such harsh conditions, higher requirements are put forward for the catalytic activity and adaptability of a catalytic electrode. Herein, we advance an ultrasimple dipping-and-heating method to engineer the surface of Ni foam (NF) into an interface-rich FeNi oxide layer and realize an exceptional oxygen evolution reaction (OER) performance.

Up-regulation of circ-SMAD7 inhibits tumor proliferation and migration in esophageal squamous cell carcinoma.

Background: Increasing evidences demonstrate that circular RNAs (circRNAs) play an important role in the development and progression of human cancers. Nevertheless, the functions and molecular mechanism of circRNAs in esophageal squamous cell carcinoma (ESCC) tumorigenesis are largely unknown. The purpose of this research is to investigate the expression and potential role of a new circular RNA named circ-SMAD7 on ESCC carcinogenesis.

Circ-DLG1 promotes the proliferation of esophageal squamous cell carcinoma.

Background: Circular RNAs (circRNAs) are a class of noncoding RNAs with closed loop structures. There has been growing evidence showing that circRNAs are involved in the pathogenesis of human diseases including various carcinomas. Our study is aimed to investigate the association between a new circRNA named circ-DLG1 (hsa_circ_0007203) and esophageal squamous cell carcinoma (ESCC) carcinogenesis.