Publications by authors named "Daokuan Liu"

Article Synopsis
  • A study was conducted to evaluate the efficacy and safety of GSK's AS04-HPV-16/18 vaccine in Chinese women aged 18-25, with an extension study 4 years later offering the vaccine to those who initially received a placebo.
  • The extension study involved 3537 women, out of 6051 total participants, and found no serious adverse events related to the vaccine, while demonstrating high efficacy rates against HPV infections and related cervical lesions.
  • The AS04-HPV-16/18 vaccine exhibited a good safety profile and provided long-term protection comparable to other international studies.
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Background: The SPF10 LiPA-25 system for human papillomavirus (HPV) detection with high analytical performance is widely used in HPV vaccine clinical trials. To develop and evaluate more valent HPV vaccines, other comparable methods with simpler operations are needed.

Methods: The performance of the LiPA-25 against that of other 7 assays, including 4 systems based on reverse hybridization (Bohui-24, Yaneng-23, Tellgen-27, and Hybribio-16) and 3 real-time polymerase chain reaction (PCR) assays (Hybribio-23, Bioperfectus-21, and Sansure-26), was evaluated in selected 1726 cervical swab and 56 biopsy samples.

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When denitrification technology using NH or urea as the reducing agent is applied to remove NOx from the flue gas, ammonium bisulfate (ABS) by-product will also be generated in the flue gas. ABS has an impact on catalyst life span, denitrification efficiency etc., air preheater and its downstream thermal equipment also have a significant negative impact due to its plugging and corrosion.

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The dry flue gas desulfurization (FGD) method was studied, which is a part of the integrated removal of multi-pollutants at medium temperatures. Although dry flue gas treatment is a simple and effective method, it is still a highly empirical-led application technology. A superior desulfurization adsorbent, fine powder of NaHCO (hereinafter called fine NaHCO), was selected by scale-up experiments.

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Objective: The Roche Cobas (Cobas) and BD Onclarity (Onclarity) human papillomavirus (HPV) assays are convenient, PCR-based, HPV DNA tests; currently, data on performance of Onclarity in Chinese women is limited. We aimed to evaluate the clinical performance of Onclarity for detecting cervical lesions in Chinese women.

Methods: In total, 1122 women were enrolled into this study.

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