Nanoarchitectonics of Fe-Doped NiS Arrays on Ni Foam from MOF Precursors for Promoted Oxygen Evolution Reaction Activity.

Oxygen evolution reaction (OER) is a critical half-reaction in electrochemical overall water splitting and metal-air battery fields; however, the exploitation of the high activity of non-noble metal electrocatalysts to promote the intrinsic slow kinetics of OER is a vital and urgent research topic. Herein, Fe-doped NiS arrays were derived from MOF precursors and directly grown on nickel foam via the traditional solvothermal way. The arrays integrated into nickel foam can be used as self-supported electrodes directly without any adhesive.

Building microcracked structure fibrous cathode coated by Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) for ultra-stable fiber-shaped aqueous zinc ions batteries.

Attributing to the advantages of intrinsic safety, high energy density, and good omnidirectional flexibility, fiber-shaped aqueous zinc ions batteries (FAZIBs), serving as energy supply devices, have multitude applications in flexible and wearable electronic devices. However, the detachment of active materials caused by bending stress generated during flexing process limits their practical application severely. To address the above issue, an effective integrated strategy employing microcracked activated cobalt hydroxide [A-Co(OH)] cathode with protective coating of poly(3,4-ethylenedioxythiophene)poly(styrenesulfonate) (PEDOT:PSS) was proposed in this work to enhance the cyclic and bending performances of FAZIBs.

Optimizing skin disease diagnosis: harnessing online community data with contrastive learning and clustering techniques.

Skin diseases pose significant challenges in China. Internet health forums offer a platform for millions of users to discuss skin diseases and share images for early intervention, leaving large amount of valuable dermatology images. However, data quality and annotation challenges limit the potential of these resources for developing diagnostic models.

Deep skin diseases diagnostic system with Dual-channel Image and Extracted Text.

Background: Due to the lower reliability of laboratory tests, skin diseases are more suitable for diagnosis with AI models. There are limited AI dermatology diagnostic models combining images and text; few of these are for Asian populations, and few cover the most common types of diseases.

Methods: Leveraging a dataset sourced from Asia comprising over 200,000 images and 220,000 medical records, we explored a deep learning-based system for Dual-channel images and extracted text for the diagnosis of skin diseases model DIET-AI to diagnose 31 skin diseases, which covers the majority of common skin diseases.

Comparative effectiveness and safety of drug therapy for chronic urticaria: a network meta-analysis and risk-benefit assessment.

Background: Chronic urticaria (CU) is a prevalent chronic skin condition characterized by recurrent wheals. Clinical guidelines recommend multiple drugs for CU treatment. Our study aims to compare the effectiveness and safety of drug therapy for CU.

Adjusting zinc deposition behaviors by a modified separator to acquire zinc anodes for aqueous rechargeable zinc-ion batteries.

Aqueous rechargeable zinc ion batteries (ARZIBs) are ideal for massive and longstanding energy storage applications because of their excellent security and low operation cost. Nevertheless, ARZIBs are subject to the severe corrosion reaction of zinc metal anodes that is derived from the thermodynamic unsteadiness of the zinc anodes in aqueous solution, as well as zinc dendrite growth originating from uncontrolled zinc deposition. Herein, we created a separator by coating a thin piece of polypropylene (PP) with a compound consisting of zinc trifluoromethanesulfonate [Zn(OTf)] and poly(vinylidene fluoride-hexafluoropropylene (PVDF-HFP).

Investigation of sulfide/nitride/phosphide treatments of hematite photoanodes for improved solar water oxidation.

Surface catalyst engineering can effectively improve the photoelectrochemical water splitting (PEC-WS) performance of semiconductor photoelectrodes. surface functional treatments can effectively reduce interface defects and improve photogenerated carrier transport. In this study, FTO/Sn@α-FeO/FeOOH photoanodes were modified with sulfide/nitride/phosphide treatments to improve their PEC-WS performance.

The abscopal effect of anti-CD95 and radiotherapy in melanoma.

Background: Radiotherapy (RT) is frequently adopted to control cancer cell proliferation, which is achieved by altering the tumor microenvironment (TME) and immunogenicity. Apoptosis of cancer cells is the major effect of radiation on tumor tissues. Fas/APO-1(CD95) receptors on the cell membrane are death receptors that can be activated by diverse factors, including radiation and integration with CD95L on CD8 T cells.

Efficacy of abrocitinib for atopic dermatitis: a meta-analysis of randomized controlled trials.

Introduction: The efficacy of abrocitinib for atopic dermatitis remains controversial.

Aim: We conducted a systematic review and meta-analysis to explore the influence of abrocitinib versus placebo on the treatment of atopic dermatitis.

Material And Methods: We searched PubMed, Embase, Web of Science, EBSCO, and Cochrane Library databases up to June 2021 for randomized controlled trials (RCTs) assessing the effect of abrocitinib versus placebo for patients with atopic dermatitis.

Facile Synthesis of NiCoS Microspheres for High-Performance Supercapacitors and Alkaline Aqueous Rechargeable NiCo-Zn Batteries.

Electrochemical energy storage devices (EESDs) have caused widespread concern, ascribed to the increasing depletion of traditional fossil energy and environmental pollution. In recent years, nickel cobalt bimetallic sulfides have been regarded as the most attractive electrode materials for super-performance EESDs due to their relatively low cost and multiple electrochemical reaction sites. In this work, NiCo-bimetallic sulfide NiCoS particles were synthesized in a mixed solvent system with different proportion of Ni and Co salts added.

Facile synthesis of mesoporous Ni Co S hollow spheres for high-performance supercapacitors and aqueous Ni/Co-Zn batteries.

Porous micro/nanostructure electrode materials have always contributed to outstanding electrochemical energy storage performances. CoS is an ideal model electrode material with high theoretical specific capacity due to its intrinsic two crystallographic sites of cobalt ions. In order to improve the conductivity and specific capacitance of CoS, nickel ions were introduced to tune the electronic structure of CoS.

Silver-Rich Hybrid Framework Iodide Based on [AgI] Clusters Displays Low-Temperature Dual Emission and Luminescence Thermochromism.

Cluster-based framework metal iodides have diverse structures and excellent luminescence properties, and show promising applications in sensing and solid-state lighting. However, the design and synthesis of these materials remain great challenges because excess I ions introduced into the synthesis systems decrease the condensation degree of M-I units. In this work, a new strategy is developed to control the condensation behavior of Ag-I units, and a new silver-rich cluster-based framework iodide [DabcoAgI(SPh)] () (Dabco = 1,4-diazabicyclo [2.

Copper Cobalt Sulfide Structures Derived from MOF Precursors with Enhanced Electrochemical Glucose Sensing Properties.

Nonenzymatic electrochemical detection of glucose is popular because of its low price, simple operation, high sensitivity, and good reproducibility. Co-Cu MOFs precursors were synthesized via the solvothermal way at first, and a series of porous spindle-like Cu-Co sulfide microparticles were obtained by secondary solvothermal sulfurization, which maintained the morphology of the MOFs precursors. Electrochemical studies exhibit that the as-synthesized Cu-Co sulfides own excellent nonenzymatic glucose detection performances.

Expression of Helper and Regulatory T Cells in Atopic Dermatitis: A Meta-Analysis.

Background: Atopic dermatitis (AD) is a common inflammatory skin disease, with the incidence peaks in infancy. A meta-analysis was performed to assess the levels of T helper type 22 (Th22) cells, T helper type 17 (Th17) cells, interleukin (IL)-17, and Tregs in peripheral blood of patients with AD.

Methods: A comprehensive literature search was performed in PubMed, Embase, China National Knowledge Internet, and Wan-fang Data from the day of inception of this study to July 2021.

Synthesis of bimetallic nickel cobalt selenide particles for high-performance hybrid supercapacitors.

Supercapacitors are known as promising excellent electrochemical energy storage devices because of their attractive features, including quick charge and discharge, high power density, low cost and high security. In this work, a series of litchi-like Ni-Co selenide particles were synthesized a simple solvothermal method, and the Ni-Co compositions were carefully optimized to tune the charge storage performance, charge storage kinetics, and conductivity for battery-like supercapacitors. Interestingly, the optimal sample NiCoSe exhibits a high capacity of 1038.

Skin Immunosenescence and Type 2 Inflammation: A Mini-Review With an Inflammaging Perspective.

Skin-resident stromal cells, including keratinocytes, fibroblasts, adipocytes, and immune cells including Langerhans cells, dendritic cells, T cells, and innate lymphoid cells, and their functional products work in concert to ensure the realization of skin barrier immunity. However, aging-induced immunosenescence predisposes the elderly to pruritic dermatoses, including type 2 inflammation-mediated. Inflammaging, characterized by chronic low level of pro-inflammatory cytokines released from senescent cells with the senescence-associated secretory phenotype (SASP), may drive immunosenescence and tangle with type 2 inflammatory dermatoses.

Efficacy and safety of ebastine dose escalation in chronic urticaria: A prospective study.

The second-generation antihistamines at licensed doses are first-line treatment in urticaria and up-dosing is recommended as second-line treatment. To assess the efficacy and safety of escalated doses of ebastine in patients with chronic urticaria (CU), we designed this study. Recruited patients with CU were treated with increasing doses of ebstine.

Analysis on the spatio-temporal evolution and influencing factors of China's grain production.

The rapid economic development and climate change have accelerated the changes in China's food production and have a potential impact on food security. In this paper, the grain sown area from 2001 to 2019 was selected to analyze the spatio-temporal evolution and driving factors of China's grain production through spatial autocorrelation analysis and geographically weighted regression. Our findings were as follows: (1) From the perspective of time characteristics, China's grain production from 2001 to 2019 experienced four stages, rapid decline, rapid growth, steady growth, and slow decline, although with an overall upward trend.

Spatio-temporal characteristics and control strategies in the early period of COVID-19 spread: a case study of the mainland China.

COVID-19 has caused huge impacts on human health and the economic operation of the world. Analyzing and summarizing the early propagation law can help reduce the losses caused by public health emergencies in the future. Early data on the spread of COVID-19 in 30 provinces (autonomous regions and municipalities) of mainland China except for Hubei, Hong Kong, Macao, and Taiwan were selected in this study.

Effect of landscape-scale farmland fragmentation on the ecological efficiency of farmland use: a case study of the Yangtze River Economic Belt, China.

Improving the ecological efficiency of farmland use (EEFU) has become an important part of ensuring food security and solving environmental pollution problems. At present, the Chinese government is actively promoting large-scale farmland transfer to reduce the level of farmer-/plot-scale farmland fragmentation (FF), so it is crucial to clarify the effect of landscape-scale FF on EEFU. This study applies the non-dynamic panel and threshold models in an empirical study of the municipal administrative regions along the Yangtze River Economic Belt (2000, 2005, 2010, and 2015).

Contact sensitization to cosmetic series of allergens in female patients with rosacea: A prospective controlled study in China.

Background: Allergic contact dermatitis to cosmetics (ACDC) complicates the diagnosis and treatment of rosacea, and is increasingly observed in daily practice.

Aims: The present study aimed to identify the contact allergens responsible for ACDC in Chinese female rosacea patients with or without suspected ACDC (SACDC).

Methods: From a total of 1267 women with rosacea, 122 with SACDC, 145 without SACDC, and 100 age-matched healthy controls without rosacea or SACDC were examined on a voluntary basis.

Electrochemical Sensors Based on Covalent Organic Frameworks: A Critical Review.

The metal-free cousins of metal-organic frameworks, covalent organic frameworks (COFs), are a class of pre-designable crystalline polymers composed of light elements and connected by strong covalent bonds. COFs are being given more and more attention in the electrochemical sensor field due to their fascinating properties, such as highly tunable porosity, intrinsic chemical and thermal stability, structural diversity, large specific surface area, and unique adsorption characteristics. However, there are still some key issues regarding COFs that need to be urgently resolved before they can be effectively applied in electrochemical sensing.