Publications by authors named "Daohe Yuan"

Article Synopsis
  • Existing mass spectrometry (MS) methods struggle to accurately characterize the composition of organic aerosol (OA) due to limitations like selective ionization and extraction issues.
  • A study examined aerosol samples from various atmospheric conditions using both electrospray ionization (ESI) and laser desorption ionization (LDI), finding that LDI simplifies sample preparation and offers better analysis of certain compounds.
  • In situ LDI proves to be particularly effective in identifying molecular compositions of OAs, especially from polluted samples, potentially improving our understanding of OA sources and impacts on the atmosphere.
View Article and Find Full Text PDF

As a tumor-suppressing protein, p53 plays a crucial role in preventing cancer development. Its utility as an early cancer detection tool is significant, potentially enabling clinicians to forestall disease advancement and improve patient prognosis. In response to the pathological overexpression of this antigen in tumors, the prevalence of anti-p53 antibodies increases in serum, in a manner quantitatively indicative of cancer progression.

View Article and Find Full Text PDF

Sauce-flavor Baijiu is one of the most complex and typical types of traditional Chinese liquor, whose trace components have an important impact on its taste and quality. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) is one of the most favorable analytical tools to reveal trace molecular components in complex samples. This study analyzed the chemical diversity of several representative sauce-flavor Baijiu using the combination of electrospray ionization (ESI) and FT-ICR MS.

View Article and Find Full Text PDF

Paramagnetically-doped polymer micelles, containing an ionizable poly(acrylic acid) (PAA) block, support high-contrast MR imaging at clinically relevant field strengths in a manner that is strongly pH responsive. A reversible switch in polymer strand charge specifically has a direct impact on local rigidity, and rotational correlation time characteristics, of the integrated Gd-chelate, driving a ∼50% amplitude switch in positive contrast.

View Article and Find Full Text PDF

Rationale: The development of appropriate analytical screening techniques for pharmaceuticals and personal care products (PPCPs) is the basis for studying the distribution and environmental impact of emerging contaminants (ECs). Mass spectrometry-based screening methods vary with the complexity of the target compounds. It is challenging to balance both positive and negative ion quantification with a low detection limit.

View Article and Find Full Text PDF

A series of tetraphenylethene (TPE) derivatives functionalized with highly potent electron-deficient perfluoroaryl iodo-triazole halogen bond (XB) donors for anion recognition are reported. H NMR titration experiments, fluorescence spectroscopy, dynamic light scattering measurements, TEM imaging and X-ray crystal structure analysis reveal that the tetra-substituted halogen bonding receptor forms luminescent nanoscale aggregates, the formation of which is driven by XB-mediated anion coordination. This anion-coordination-induced aggregation effect serves as a powerful sensory mechanism, capable of luminescence chloride sensing at parts per billion concentration.

View Article and Find Full Text PDF
Article Synopsis
  • A biomedical contrast agent improves the visibility of targeted areas in physiological imaging, with mesoporous silica nanoparticles (MSNs) emerging as a versatile option due to their customizable features.
  • The review highlights various structural types and synthesis techniques for MSNs, along with innovative approaches for modifying their surfaces.
  • It also examines recent uses of MSNs in biomedical imaging, focusing on magnetic resonance and optical imaging, as well as their effectiveness in combining different imaging methods.
View Article and Find Full Text PDF