Publications by authors named "Daogen Yin"
Article Synopsis
- SGLT2 inhibitors and GLP-1 receptor agonists have been shown to improve heart and kidney outcomes in type 2 diabetes patients, but their relative efficacy is still unclear.
- A meta-analysis of 14 cardiovascular and renal outcome trials revealed that sotagliflozin and subcutaneous semaglutide were among the most effective drugs for reducing major adverse cardiovascular events, hospitalization for heart failure, and other key outcomes.
- The findings indicate that sotagliflozin, subcutaneous semaglutide, and albiglutide are particularly effective in lowering the risk of major cardiovascular events compared to other treatments.
The association between sodium-glucose cotransporter 2 inhibitors (SGLT2is) and various cardiovascular and respiratory diseases is unestablished. This meta-analysis aimed to explore whether use of SGLT2is is significantly associated with the occurrences of 80 types of cardiovascular diseases and 55 types of respiratory diseases. Large randomized trials of SGLT2is were included in analysis.
View Article and Find Full Text PDFBackground: The factors affecting the efficacy of gliflozins in patients with heart failure (HF) are not clear. We aimed to evaluate the effects of 11 important factors on the efficacy of gliflozins in HF patients.
Methods: Randomized trials assessing gliflozins in HF patients were included.
The PIONEER and SUSTAIN serial trials are designed to assess the efficacy outcomes with semaglutide in patients with type 2 diabetes, but are not powered to assess various safety outcomes. We sought to assess the risk of semaglutide in leading to various serious adverse events (SAEs) in patients with type 2 diabetes. Studies eligible for inclusion were the PIONEER and SUSTAIN trials of semaglutide.
View Article and Find Full Text PDF[Effect of probiotic supplementation during pregnancy and infancy in preventing atopic dermatitis in children: a Meta analysis].
Zhongguo Dang Dai Er Ke Za Zhi
January 2019
Objective: To systematically review the effect of probiotic supplementation during pregnancy and infancy in preventing atopic dermatitis in children.
Methods: RevMan5.3 was used to perform a Meta analysis of randomized controlled trials on the effect of probiotic supplementation during pregnancy and infancy in preventing atopic dermatitis in children published between January 2008 and May 2018 across the world.