Survival to hospital discharge and neurological outcomes with targeted temperature management after in-hospital cardiac arrest: a systematic review and meta-analysis.

Background: Multiple randomized controlled trials have shown that targeted temperature management (TTM) has favorable effects in out-of-hospital cardiac arrest. However, the benefit of TTM in patients with in-hospital cardiac arrest (IHCA) remains to be verified.

Methods: The PubMed, Cochrane Library, and EMBASE databases were searched for clinical studies with the primary outcomes of survival to hospital discharge and neurological outcomes.