Publications by authors named "Dao Thi Hong Pham"
Background: Antibiotic resistance of Helicobacter pylori (H. pylori) is increasing worldwide, with geographical variations, impacting the treatment outcomes. This study assessed the antibiotic resistance patterns of H.
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- Amoxicillin-resistant strains of Helicobacter pylori (H. pylori) are increasing in Vietnam, making it harder to treat infections with this antibiotic, which prompted the study to explore the extent of this resistance and its genetic causes.
- The study involved 308 patients with dyspepsia, using various diagnostic tests, including E-tests to check for amoxicillin susceptibility, and real-time PCR to detect genetic mutations linked to resistance.
- Results showed that 25.7% of H. pylori strains were primarily resistant to amoxicillin, and specific mutations in the pbp1A gene were significantly associated with this resistance, highlighting the genetic diversity among resistant and sensitive strains.