Publications by authors named "Dao Sen Wang"
Objectives: Evidence on the link between long-term ambient particulate matter (PM) exposures and childhood sleep disorders were scarce. We examined the associations between long-term exposures to PM and PM (PM with an aerodynamic equivalent diameter <2.5 μm and <1 μm, respectively) with sleep disorders in children.
View Article and Find Full Text PDFBackground: Hepatitis C virus (HCV) infection can now be cured with well-tolerated direct-acting antiviral (DAA) therapy. However, a potential barrier to HCV elimination is the emergence of resistance-associated substitutions (RASs) that reduce the efficacy of antiviral drugs, but real-world studies assessing the clinical impact of RASs are limited. Here, an analysis of the impact of RASs on retreatment outcomes for different salvage regimens in patients nationally who failed first-line DAA therapy is reported.
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- The study investigates the link between exposure to chlorinated paraffins (CPs), a type of persistent organic pollutant, and the prevalence of allergic diseases in children and adolescents in the Pearl River Delta region of China.
- A survey with 131,304 participants highlighted that increased levels of CPs in particulate matter are significantly associated with allergic rhinitis, atopic eczema, and allergic conjunctivitis, showing specific odds ratios for each condition.
- The research suggests that overweight and obese individuals may be at an even higher risk for these allergic diseases; however, further studies are necessary to confirm these findings and explore the underlying mechanisms.
Article Synopsis
- The study investigated the link between home renovations and sleep problems in children aged 6-18, using data from over 186,000 participants in the National Chinese Children Health Study.
- Results showed that about 48% of the children had been exposed to recent home renovations, and these children had significantly higher odds (30% more likely) of experiencing sleep disorders compared to those not exposed.
- The impact on sleep problems varied based on the types of renovation materials used and was influenced by the children's age and sex, indicating that these factors play a role in how renovations affect sleep health.
Anthropogenic heat has been reported to have significant health impacts, but research on its association with childhood adiposity is still lacking. In this study, we matched the 2008-2012 average anthropogenic heat flux, as simulated by a grid estimation model using inventory methods, with questionnaire and measurement data of 49,938 children randomly recruited from seven cities in Northeast China in 2012. After adjusting for social demographic and behavioral factors, we used generalized linear mixed-effect models to assess the association between anthropogenic heat flux and adiposity among children.
View Article and Find Full Text PDFDirect acting antivirals (DAAs) have revolutionized hepatitis C virus (HCV) treatment, but drug resistance could undermine proposed global elimination targets. Real-world studies are needed to inform the impact of widespread DAA treatment on antiviral resistance in the community. The prevalence and range of posttreatment resistance-associated substitutions (RASs) was determined in Australian patients with open access to DAAs through a wide range of prescribers.
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